P. Yong

Abstract Introduction Neuroproliferative vestibulodynia (NPV) is a chronic genital pain condition characterized by severe vestibular allodynia and hyperalgesia. The clinically suspected diagnosis of NPV is confirmed in excised vestibular ti…

Objective Multiple forms of endometriosis have been shown to harbour somatic cancer-driver alterations. Previous studies have focused on the inter-patient heterogeneity of genetic alterations in endometriosis, analyzing lesions collected fr…

Deep dyspareunia affects 50% of women with endometriosis and has significant negative effects on relationships and sexual function. Previous research has identified painful bladder syndrome as a significant contributor to deep dyspareunia w…

Endometriosis is a common gynecological condition affecting one in 10 reproductive-aged women. More than half of these women report moderate-to-severe deep dyspareunia, defined as pelvic pain experienced with deep penetration during sexual …

Endometriosis is a chronic disease occurring during the reproductive stage of women.Although there is only limited association between endometriosis and gynecological cancers with regard to clinical features, the molecular basis of the rela…

The etiology of endometriosis-associated deep dyspareunia (DD) may be due to direct disease-specific factors (e.g. location or invasiveness of disease) and/or to indirect contributors such as bladder/pelvic floor dysfunction. We aimed to de…

The clinical presentation of endometriosis is highly heterogeneous. In a landmark study we have shown somatic cancer-driver mutations in deep infiltrating endometriosis, with at least one case having multiple sites harboring the same driver…

Endometriosis is a common gynecological disease and precursor of clear cell and endometrioid ovarian carcinomas. We recently demonstrated that one form of endometriosis with little malignant potential, deep infiltrating endometriosis (DE), …