Marlen Tellez Santos

No ORCID on file · 13 papers in corpus · active 2014-2020

Study types

  • article 13

Condition tags

  • endometriosis 5
article 2020
CD44 variant 6 is involved in the attachment and invasion of endometrial cells to peritoneum
F&S science ·doi:10.1016/j.xfss.2020.08.002

Objective To study the effects of CD44 standard (CD44s), CD44v3, and CD44v6 overexpression (OE) on immortalized human endometrial epithelial (iEECs) and stroma cells (human endometrial stromal cells [hESCs]) using in vitro assays and a nude…

article 2020
Inhibition of Hyaluronic Acid Synthesis Decreases Endometrial Cell Attachment, Migration, and Invasion
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00100-w

To characterize the effects of 4-methylumbelliferone (4-MU) on expression of the hyaluronic acid (HA) system and on attachment, migration, and invasion of endometrial epithelial (EECs) and stroma cells (ESCs) to peritoneal mesothelial cells…

article 2019
3332 Overexpression of CD44 is involved in the development of the early endometriotic lesion in a xenograft model
·doi:10.1017/cts.2019.255

OBJECTIVES/SPECIFIC AIMS: Previously, we showed decreased development of endometriotic lesions in CD44 knockout mice compared to control.(1) CD44 has 10 different variants and a standard form. Menstrual endometrial cells (MECs) from women w…

article 2019
Overexpression of CD44v6 is involved in the development of the early endometriotic lesion in a xenograft model
·doi:10.1016/j.fertnstert.2019.07.941
article 2018
Endometrial attachment and invasion is decreased with estrogen receptor beta knock down
·doi:10.1016/j.fertnstert.2018.07.1105
article 2018
Endometrial cell invasion is decreased with inhibition of hyaluronic acid synthesis
·doi:10.1016/j.fertnstert.2018.07.1094
article 2018
Knockdown of cd44 decreases attachment but not invasion of endometrial epithelial cells
·doi:10.1016/j.fertnstert.2018.07.1089
article 2018
Overexpression of CD44 is involved in the development of the early endometriotic lesion
·doi:10.1016/j.fertnstert.2018.07.1090
article 2018
The Hyaluronic Acid System is Intact in Menstrual Endometrial Cells in Women With and Without Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118766257

ObjectiveTo characterize the production and degradation of hyaluronic acid (HA) in menstrual endometrial epithelial cells (EECs) and endometrial stromal cells (ESCs) in women with and without endometriosis. To identify the presence of CD44,…

article 2017
2114
Journal of clinical and translational science ·doi:10.1017/cts.2017.203

OBJECTIVES/SPECIFIC AIMS: To further elucidate the role of estrogen receptor β (ER-β) in the early endometriotic lesion attachment. METHODS/STUDY POPULATION: EECs were immortalized using a telomerase vector. Immortalized cells and parental …

article 2017
The role of estrogen receptor beta in development of the early endometriotic lesion
·doi:10.1016/j.fertnstert.2017.07.589
article 2015
Impaired Development of Early Endometriotic Lesions in CD44 Knockout Mice
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115594022

Previous studies have shown endometrial cell (EC) CD44 and peritoneal mesothelial cell (PMC)-associated hyaluronan (hyaluronic acid [HA]) are involved in the attachment of endometrial stroma and epithelial cells to peritoneal mesothelium. H…

article 2014
Endometrial epithelial cell expression of estrogen receptor isoforms alpha and beta alters attachment to peritoneal mesothelial cells
·doi:10.1016/j.fertnstert.2014.07.988