In recent years, nanotechnology has revolutionized global healthcare and has been predicted to exert a remarkable effect on clinical medicine. In this context, the clinical use of nanomaterials for cancer diagnosis, fertility preservation, …
It is well established that there is a heritable element of susceptibility to chronic human ailments, yet there is compelling evidence that some components of such heritability are transmitted through non-genetic factors. Due to the complex…
Effects of danazol plus testosterone enanthate on rabbit vas deferens are investigated. Seminal, biochemical tissue and histological studies were performed. Sperm motility was markedly impaired with the advancement of treatment. At the end …
A combination of danazol (15 mg/kg b.w./day; oral) plus TE (5 mg/kg b.w./15 days; i.m.) was investigated for reversible inhibition of testicular function in rabbit. Testicular histology and biochemistry were studied before, during (30, 60 &…
The effects of Danazol on the reproductive organs of female rats have been investigated. Danazol brings about suppression of ovarian weight and distinct follicular atresia indicating antigonadotropic properties. Increase in uterine weight a…
Antifertility and oestrogenic effects of Danazol have been studied in female mice. Danazol brings about suppression of ovarian weight, presumably by inhibiting gonadotropin secretion. Enlargement of uterine horns and well defined vaginal ke…
The properties of a new synthetic steroid 17-alpha-pregn-4-en-20-yno-(23-d)isoxazol-17-ol (danazol) were investigated in ovariectomized mice and compared with estrogen-treated spayed mice. Danazol alone or in combination with estradiol dipr…