Yu SHAO

No ORCID on file · 4 papers in corpus · active 2018-2025

Study types

  • article 3
  • review 1

Condition tags

  • adenomyosis 3
  • endometriosis 1
  • infertility 1
article 2025
Study on the mechanism of <italic>Neiyi Kangfu Tablet</italic> (内异康复片) in ameliorating fibrosis of adenomyosis based on the IL-6/STAT3 pathway
·doi:10.70976/j.1008-0805.szgygy-2025-1003

目的 探讨内异康复片对小鼠子宫腺肌病纤维化的影响，并探讨其对IL-6/STAT3信号通路的调控作用。 方法 采用枸橼酸他莫昔芬滴喂的方法制备子宫腺肌病纤维化小鼠模型，70日龄小鼠采用低、中、高剂量的内异康复制剂及地诺孕素分别给药治疗，灌胃期间比较各组小鼠不同时间段的热痛阈值，灌胃治疗8周后取样，HE及Masson染色观察子宫组织病理学，Western Blot检测小鼠子宫组织中STAT3、p-STAT3的蛋白表达含量，ELISA测定血清中IL-6、TGF-β1、MCP-…

article 2025
Study on the mechanism of <italic>Neiyi Kangfu Tablet</italic>（内异康复片） in regulating macrophage polarization in adenomyosis mice
·doi:10.70976/j.1008-0805.szgygy-2025-2201

目的 探索内异康复片通过JAK2/STAT3通路调控子宫腺肌病小鼠巨噬细胞极化的作用机制。 方法 将造模成功的子宫腺肌病小鼠随机分为模型组、内异康复低/中/高剂量组、地诺孕素组。另设对照组。干预8周。采用热测痛仪评估疼痛敏感度；HE染色观察子宫病理形态；RT-qPCR和Western blot测定JAK2/STAT3通路相关因子mRNA的表达及磷酸化水平；免疫组化分析iNOS、Arg-1、IL-12A、IL-10的表达差异。 结果 模型组小鼠痛觉敏感度升高（P<0.…

review 2023
Exosomes: potential diagnostic markers and drug carriers for adenomyosis
Frontiers in pharmacology ·doi:10.3389/fphar.2023.1216149

Adenomyosis is a common benign gynecological disorder and an important factor leading to infertility in fertile women. Adenomyosis can cause deep lesions and is persistent and refractory in nature due to its tumor-like biological characteri…

article 2018
Endometriosis does not confer improved prognosis in ovarian clear cell carcinoma: a retrospective study at a single institute
Journal of ovarian research ·doi:10.1186/s13048-018-0425-9

BACKGROUND: Considered as the precursor lesion of a subset of ovarian clear cell carcinoma (OCCC), the prognostic role of endometriosis in OCCC patients remains controversial. This study aimed to investigate the prognostic role of coexistin…