Jäger W

No ORCID on file · 3 papers in corpus · active 1997-2021
2021
Altered Profile of E1-S Transporters in Endometrial Cancer: Lower Protein Levels of ABCG2 and OSTβ and Up-Regulation of SLCO1B3 Expression.
International journal of molecular sciences ·doi:10.3390/ijms22083819

Endometrial cancer (EC) is associated with increased estrogen actions. Locally, estrogens can be formed from estrone-sulphate (E1-S) after cellular uptake by organic anion-transporting polypeptides (OATP) or organic anion transporters (OAT)…

2013
The sulfatase pathway for estrogen formation: targets for the treatment and diagnosis of hormone-associated tumors.
Journal of drug delivery ·doi:10.1155/2013/957605

The extragonadal synthesis of biological active steroid hormones from their inactive precursors in target tissues is named "intracrinology." Of particular importance for the progression of estrogen-dependent cancers is the in situ formation…

1997
Distribution of radiolabelled anti-CA125 monoclonal antibody OC125-F(ab)2-fragment following resection guided by antibodies (REGAJ) in ovarian cancer patients.
Journal of clinical laboratory analysis ·doi:10.1002/(sici)1098-2825(1997)11:2<94::aid-jcla5>3.0.co;2-k

Ovarian cancer is a highly malignant tumor of mainly postmenopausal women. The long-term prognosis of this malignancy is largely determined by micrometastasis present at the time of second-look surgery. In general, patients face a poor outc…