R. Wu

INTRODUCTION: Disparities exist within the diagnosis and the management of individuals with endometriosis. Early biased research reported White race as a risk factor for developing endometriosis. Recent studies demonstrate that non-White pa…

Abstract Study question Is SPHK1 involved in the progression of endometriosis and its mechanisms? Summary answer SPHK1 knockdown induces excessive stress and autophagy via PERK degradation in ectopic endometrial stromal cells. What is known…

ObjectiveTo investigate the involvement of inflammation in the development of endometriosis.DesignCase-control study to investigate the association between endometriosis and four inflammation-related genes: interleukin (IL)-6, IL-10, IL-1 b…

OBJECTIVE: To investigate the effects of mifepristone on expression of estrogen receptor (ER) and progesterone receptor (PR) in cultured human eutopic and ectopic endometria. METHODS: Endometrial (n = 22) and endometriotic (n = 12) tissues,…

OBJECTIVE: To compare the efficacy and safety of mifepristone and danazol after conservative surgery in the treatment of patients with endometriosis. METHODS: Sixty-one patients with endometriosis (RAFS stage I-IV ) after conservative surge…

OBJECTIVE: To investigate the regulatory effects of mifepristone and progesterone on the secretion of interleukin-6 (IL-6) by endometrial and endometriosis cells in vitro. METHODS: Primary cultures of eutopic and ectopic endometrial cells f…