Ako Yokoi

No ORCID on file · 18 papers in corpus
other 2025
Cancers ·doi:10.3390/cancers17020184

BACKGROUND/OBJECTIVES: S100A4, a small calcium-binding protein, promotes metastasis in a variety of human malignancies, but little is known about its involvement in ovarian clear cell carcinoma (OCCC). Herein, we characterized the functiona…

lab-animal 2023
Molecular oncology ·doi:10.1002/1878-0261.13503

Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) is a scaffold protein that is required for epithelial polarity. Knockout (KO) of membranous EBP50 (Me-EBP50) in ovarian clear cell carcinoma (OCCC) cells induced an epithelial-mesenchym…

lab-animal 2019
·doi:10.6084/m9.figshare.7950836

Figure S1. Responsiveness for TGF-β1 and endogenous Nodal status in the cell line investigated. (A) Western blot for the indicated proteins after treatment of ES-2, OVISE, TOV-21G, and Ishikawa cells with 2 ng/mL TGF-β1 for the times indica…

lab-animal 2019
·doi:10.6084/m9.figshare.7950836.v1

Figure S1. Responsiveness for TGF-β1 and endogenous Nodal status in the cell line investigated. (A) Western blot for the indicated proteins after treatment of ES-2, OVISE, TOV-21G, and Ishikawa cells with 2 ng/mL TGF-β1 for the times indica…

lab-animal 2019
·doi:10.6084/m9.figshare.7950845

Figure S2. Overexpression of Nodal enhances susceptibility to apoptosis in OEmCa cells. (A) After treatment of the stable Nodal-expressing Ish-NoD and mock cells with 1 μg/mL Dox for the times indicated, cells undergoing apoptosis (sub-G1) …

lab-animal 2019
·doi:10.6084/m9.figshare.7950845.v1

Figure S2. Overexpression of Nodal enhances susceptibility to apoptosis in OEmCa cells. (A) After treatment of the stable Nodal-expressing Ish-NoD and mock cells with 1 μg/mL Dox for the times indicated, cells undergoing apoptosis (sub-G1) …

lab-animal 2019
·doi:10.6084/m9.figshare.7950851.v1

Figure S3. Association between TGF-β1 with Bcl2/Bax status in the stable Nodal-expressing Ish-NoD cells. Left: western blot assay for the indicated proteins after treatment of Ishikawa cells with 2 ng/mL TGF-β1 for the times indicated. Righ…

lab-animal 2019
·doi:10.6084/m9.figshare.7950851

Figure S3. Association between TGF-β1 with Bcl2/Bax status in the stable Nodal-expressing Ish-NoD cells. Left: western blot assay for the indicated proteins after treatment of Ishikawa cells with 2 ng/mL TGF-β1 for the times indicated. Righ…

lab-animal 2019
·doi:10.6084/m9.figshare.7950857

Figure S4. Association between overexpression of Nodal and cell proliferation in OEmCa. (A) Two independent stable Nodal-expressing Ish-NoD cell lines and mock cells were seeded at low density. The cell numbers are presented as mean ± SD. P…

lab-animal 2019
·doi:10.6084/m9.figshare.7950857.v1

Figure S4. Association between overexpression of Nodal and cell proliferation in OEmCa. (A) Two independent stable Nodal-expressing Ish-NoD cell lines and mock cells were seeded at low density. The cell numbers are presented as mean ± SD. P…

other 2019
·doi:10.6084/m9.figshare.7950863.v1

Figure S5. Association of clinical stages with the indicated factors in OCCCa (upper) and OEmCa (lower). (TIF 758 kb)

other 2019
·doi:10.6084/m9.figshare.7950863

Figure S5. Association of clinical stages with the indicated factors in OCCCa (upper) and OEmCa (lower). (TIF 758 kb)

other 2019
Human pathology ·doi:10.1016/j.humpath.2019.04.001

We focused on specific molecular events during the development of endometriosis-associated ovarian endometrioid carcinoma (OEmCa) and ovarian clear cell carcinoma (OCCCa). Alterations in β-catenin (encoded by CTNNB1) and microsatellite inst…

lab-animal 2019
·doi:10.6084/m9.figshare.c.4459337

Abstract Background Expression of Nodal, a member of the TGF-β superfamily, is commonly absent in differentiated tissues, while its re-expression occurs in a variety of human malignancy. However, little is known about its involvement in ova…

other 2019
BMC cancer ·doi:10.1186/s12885-019-5539-y

BACKGROUND: Expression of Nodal, a member of the TGF-β superfamily, is commonly absent in differentiated tissues, while its re-expression occurs in a variety of human malignancy. However, little is known about its involvement in ovarian tum…

lab-animal 2019
·doi:10.6084/m9.figshare.c.4459337.v1

Abstract Background Expression of Nodal, a member of the TGF-β superfamily, is commonly absent in differentiated tissues, while its re-expression occurs in a variety of human malignancy. However, little is known about its involvement in ova…

lab-animal 2017
Cell communication and signaling : CCS ·doi:10.1186/s12964-017-0211-0

BACKGROUND: The left-right determination factor (LEFTY) is a novel member of the TGF-β/Smad2 pathway and belongs to the premenstrual/menstrual repertoire in human endometrium, but little is known about its functional role in endometrial car…

other 2017
Oncotarget ·doi:10.18632/oncotarget.18882

To identify proteins involved in ovarian clear cell carcinoma (OCCCa), shotgun proteomics analysis was applied using formalin-fixed and paraffin-embedded samples of ovarian carcinoma. Analysis of 1521 proteins revealed that 52 were differen…