Additional file 3: of Nodal induces apoptosis and inhibits proliferation in ovarian endometriosis-clear cell carcinoma lesions

Miura, Rinako, Ako Yokoi, Matsumoto, Toshihide, Oguri, Yasuko, Hashimura, Miki, Tochimoto, Masataka, Kajita, Sabine, Saegusa, Makoto
2019 · doi:10.6084/m9.figshare.7950851.v1 · W6939729806
Lab / animal OA: green CC0
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Western blot analysis of stable Nodal-expressing Ishikawa cells revealed that TGF-β1 treatment modulates the Bcl2/Bax protein ratio, indicating an association between TGF-β1 signaling and apoptosis regulation in ovarian endometriosis-clear cell carcinoma.

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Abstract

Figure S3. Association between TGF-β1 with Bcl2/Bax status in the stable Nodal-expressing Ish-NoD cells. Left: western blot assay for the indicated proteins after treatment of Ishikawa cells with 2 ng/mL TGF-β1 for the times indicated. Right: values of endogenous bcl2 relative to bax protein were calculated by normalization to β-actin in Ishikawa cells after 2 ng/mL TGF-β1 for the times indicated. (TIF 1720 kb)

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endometriosis

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