R. B. Greenblatt

Menopausal symptoms are a consequence of the decline in sex hormone production, and hormone replacement therapy aims not only to relieve these symptoms but also to prevent the development of diseases of old age such as osteoporosis. The gen…

The efficacy of therapeutic doses of Provest (10 mg medroxyprogesterone acetate .05 mg ethinyl estradiol) in controlling adolescent menstrual disorders was evaluated in 19 girls. Treatment for 3-6 months satisfactorily prevented amenorrhea-…

Improved diagnostic procedures and use of a new steroidal agent, danazol (Danocrine), should reduce the need for surgical intervention in fibrocystic breast disease. Thermography, a non-invasive procedure that may be used with impunity, may…

Three groups of women with benign breast disease were treated with danazol for 3 to 6 months. Doses of 100 mg per day were given to 40 patients, 200 mg to 55, and 400 mg to 35. The age range of the patients was 20 to 48 years. The patients …

Danazol, an interesting pharmacologic steroid 'in search of a disease', was first used by my group in the management of endometriosis because of the marked anti-endometrial effects found during clinical trials. The results in alleviating dy…

Benign breast disease, aside from fibroadenomas and intraductal papillomas, frequently responds favorably to hormonal therapy. Although the use of estrogen, androgens, and progestogens often proves useful, danazol, in our hands, was found m…

Forty-nine women diagnosed as having pelvic endometriosis were treated with 800 mg of danazol/day for a mean duration of 6 months. The average length of the follow-up period was 78 months. Side effects were minimal, and regular ovulatory me…

One hundred thirty-five women with benign breast disease (BBD) were treated with danazol, an impeded androgen. Their ages ranged from 19 to 60 years (mean age, 30). The dose varied from 100 to 800 mg per day for 90 to 180 days, depending up…

Danazol, an impeded androgen with moderate antigonadotropin properties, was administered to 58 patients with a variety of benign breast disorders. The disturbances were present from 3 months to 20 years; the ages ranged from 21 to 50 years.…

Danazol (2-3-isoxazol-17alpha-ethinyl-testosterone) was prescribed to 42 normally cycling women some endometriosis patients some primary and secondary infertility patients 6 girls with precocious puberty several women with breast disorders …

The past present and future of the oral contraceptive pill is summarized broadly including ancient history and efficacy of traditional contraceptives and use of early estrogen treatment for dysmennorhea (1940-1952). The present development …