D Mavrelos

Research questionWhat is the relationship between antral follicle count (AFC) and chronological age, and what are the expected values for AFC?DesignThis was a retrospective cohort study at a specialist gynaecological ultrasound centre in Lo…

Abstract Study question What is the impact of prolonged downregulation with GnRH analogue (GnRHa) on uterine peristalsis in women with moderate/severe adenomyosis undergoing frozen-thawed embryo transfer? Summary answer Women with moderate/…

OBJECTIVE: To determine the natural progression of ovarian endometrioma in women who are managed expectantly. METHODS: This was a retrospective cohort study of 83 women with evidence of ovarian endometrioma who were managed expectantly bet…

Adenomyosis is a benign invasion of endometrial glands and stroma into the uterine myometrium. [1, 2]. It can present with heavy and painful menstrual bleeding or be asymptomatic [2-4]. Over last three decades the diagnosis of adenomyosis h…

Abstract Study question Do women with adenomyosis have altered uterine peristalsis? Summary answer Women with adenomyosis have altered uterine peristalsis on transvaginal sonography (TVS), as measured using optical flow for motion quantific…

INTRODUCTION: Adenomyosis can adversely reduce chances of pregnancy in couples undergoing assisted conception. We aim to evaluate the effect of two different downregulation protocols on the reproductive outcomes in women with moderate and s…

Abstract Study question What is the prevalence of abnormal findings on transvaginal ultrasound scan (TVS) in a population of women presenting with subfertility to a One-Stop fertility clinic? Summary answer Two thirds of women in our popula…

STUDY QUESTION: Can the priorities for future research in infertility be identified? SUMMARY ANSWER: The top 10 research priorities for the four areas of male infertility, female and unexplained infertility, medically assisted reproduction…

Key content The impact of benign ovarian cysts on a woman’s fertility is dependent on the nature, size, number, bilaterality and risk of recurrence of the cyst(s). Children and adolescents presenting with pathological ovarian cysts require …

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STUDY QUESTION: Can the priorities for future research in infertility be identified? SUMMARY ANSWER: The top 10 research priorities for the four areas of male infertility, female and unexplained infertility, medically assisted reproduction…

Additional file 2. Results of TMT-based LC-MS/MS profiling with candidate scoring.

To examine the natural history of DE in women that are managed expectantly. This was a retrospective cohort study of 87 women with evidence of DE, who were managed expectantly for a minimum of 6 months. All women attended for a minimum of t…

STUDY QUESTION: What would be a potential impact of implementing the new ESHRE/European Society of Gynaecological Endoscopy (ESGE) female genital anomalies classification system on the management of women with previous diagnosis of arcuate …

Our primary aim was to describe the frequency of abnormal findings on transvaginal ultrasound scan (TVS) in a population of couples presenting with infertility to a tertiary unit. Our secondary objective was to identify which pathologies we…

Our study examined the impact of adenomyosis on the chance of clinical pregnancy after IVF and embryo transfer (IVF-ET). This was a prospective multicentre study from April 2013 to October 2015. We included 375 women with history of inferti…

The aim of this study was to explore patient experiences and perceptions of adenomyosis.

To examine the impact of adenomyosis on outcome of in vitro fertilisation cycle and whether specific features of adenomyosis are associated with poor outcome. This is a prospective observational study in a population of women undergoing the…

To examine the impact of adenomyosis on obstetric outcome after in vitro fertilisation. This is a prospective observational study in a population of women undergoing their first IVF cycle in two London teaching hospitals between April 2013 …

study question: Is the presence of adenomyosis associated with menorrhagia? summaryanswer: Therewas no significant association between adenomyosis andmenorrhagia, but therewas a significant positive correl-ation between the severity of aden…

OBJECTIVE: To investigate the association between the ultrasound features of adenomyosis and the severity of menstrual pain. METHODS: This was a prospective observational study set in the general gynecology clinic of a university teaching h…

Ovarian endometriomas are classified as benign ovarian lesions. During pregnancy endometriomas may undergo major morphological changes which are referred to as ‘decidualisation'. Decidualised ovarian endometrioma may resemble malignant ovar…