Sylvie Defrère

No ORCID on file · 32 papers in corpus
other 2008
Gynecologic and obstetric investigation ·doi:10.1159/000127447

BACKGROUND/AIMS: The aim of this study was to induce endometriosis in female rhesus macaques (Macaca mulatta) for research purposes. METHODS: Three female monkeys from 4 to 4.5 years of age underwent three consecutive attempts at endometri…

other 2007
Gynecologic and obstetric investigation ·doi:10.1159/000111148

BACKGROUND: In vitro studies suggest that the transcription factor nuclear factor-kappa B (NF-kappaB) is implicated in the transduction of proinflammatory signals in endometriosis. The aim of this study was to investigate the involvement of…

other 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.06.015

Endometriosis is characterized by pelvic inflammation that shows an increased number of activated peritoneal macrophages and their secreted products such as cytokines, growth factors, and angiogenic factors. Our results show that activation…

other 2007
Molecular human reproduction ·doi:10.1093/molehr/gam033

Red (active), black and white endometriotic lesions are characteristic of peritoneal endometriosis. The transcription factor nuclear factor-kappa B (NF-kappaB) activates proinflammatory, proliferative and antiapoptotic genes in many cell ty…

other 2006
Human Reproduction ·doi:10.1093/humrep/del261

BACKGROUND: Iron deposits are characteristic of endometriotic lesions, and pelvic iron concentrations are higher in endometriosis patients than in women without endometriosis. In this study, the effect of iron overload and iron chelation on…

2006
·doi:10.1093/humrep/del115
other 2005
Human Reproduction ·doi:10.1093/humrep/dei387

BACKGROUND: In animal models of endometriosis, the identification and quantification of lesions originating from human endometrium is often hampered by the small size of the implants and their embedding in murine tissue. The purpose of the …