A. A. Stepanyan

Endometriosis is a gynecological disorder characterized by the presence of tissue that is morphologically and functionally similar to the endometrium, but located outside the uterine cavity. The disease is chronic and prone to recurrence. A…

The aim of this review is to analyse contemporary scientific evidence concerning the role and significance of macrophage polarisation in the pathogenesis of endometriosis. Particular emphasis is placed on the molecular and cellular mechanis…

Adenomyosis is a disease associated with the formation and growth of endometrial tissue in the myometrium. Ectopic foci cause hypertrophy and hyperplasia of the surrounding endometrium, which leads to diffuse enlargement of the uterus. Such…

Endometriosis is a gynecological disease characterized by the presence of tissue with morphological and functional properties similar to the endometrium outside the uterine cavity. This pathology affects about 10% of women of reproductive a…

Endometriosis is a pathological process in which the presence of tissue is determined by morphological and functional properties similar to the endometrium outside the uterine cavity. The most common symptom of endometriosis is chronic pelv…

Dinitrosyl iron complexes (DNIC) with glutathione exert a cytotoxic effect on endometrioid tumours in rats with surgically induced experimental endometriosis. Intraperitoneal treatment of rats (Group 1) with DNIC (12.5μmoles/kg, daily, for …

A study was made of the effect of binuclear dinitrosyl iron complexes (DNIC) with glutathione in rats with experimental endometriosis. The latter was induced in an autotransplantation model, where two fragments of endometrium with myometriu…

Administration of dinitrosyl iron complexes (DNIC) with cysteine suppressed the development of experimental (surgically induced) endometriosis in rats: the mean size of endometrioma was 1.85 times smaller if 0.5 mL of a 5 mM aqueous solutio…