BACKGROUND: Endometriosis is a chronic estrogen-dependent inflammatory disorder associated with pelvic pain, infertility, and an increased risk of endometriosis-associated ovarian cancer. Despite extensive research, its molecular mechanisms…
OBJECTIVE: To evaluate the safety and pharmacokinetics/pharmacodynamics of AMY109, an anti-interleukin-8 recycling antibody in a first-in-human phase 1 trial in healthy volunteers (HVs) and patients with endometriosis. DESIGN: A multicente…
BACKGROUND: Early dietary intake enhanced recovery after surgery (ERAS). There remains a gap in the recognition and implementation of early diet after surgery in medical institutions in Taiwan. This study aimed to investigate whether early …
Endometriosis, manifested by pain and infertility, is a chronic inflammatory disease, associated with a large disability of daily living, causing a socio-economic diastrophic problem and burden. The main goal of therapy attempts to reduce p…
OBJECTIVE: To evaluate the efficacy of different hormone therapies in preventing postoperative endometrioma recurrence. DATA SOURCES: The MEDLINE, COCHRANE, and Embase electronic databases were searched from inception to 30 April 2021. ME…
Adhesions, characterized by fibrin deposition leading to fibrous tissue connections (adherence tissues) between various tissue planes or organs, as part of internal healing process and inflammatory reactions passing through the different bu…
This study aims to analyze the patient profile and presentation of endometriosis-related hemorrhagic ascites and review its management to raise awareness among gynecologists and improve treatment strategies. We present a case report and eng…
OBJECTIVE: Endometriosis-associated epithelial ovarian cancer (EOC) often includes clear cell carcinoma and endometrioid-type carcinoma. Due to the low incidence of primary mucinous EOC and absence of association between endometriosis and p…
Clear cell carcinoma of the ovary (ovarian clear cell carcinoma [OvCCC]), one of subtypes of epithelial ovarian carcinoma (EOC), is often accompanied with endometriosis, which is also called as endometriosis-associated EOC (EAEOC) and frequ…
The use of weekly chemotherapy for the treatment of patients with advanced-stage serous-type epithelial Tubo-ovarian cancer (ETOC), and primary peritoneal serous carcinoma (PPSC) is acceptable as the front-line postoperative chemotherapy af…
Endometriosis is a multifactorial and chronic inflammatory disease, involving more than 10% of women of reproductive age, contributing to a heavy burden of socioeconomic health problems, such as pelvic adhesion, chronic pelvic pain, inferti…
Total hysterectomy (TH) may be one of the most frequent surgeries in women during their life-span period, although the recent trends have become more apparent in the use of fertility-sparing surgery (organ-preservation strategy) in place of…