Sakhila K. Banu

No ORCID on file · 37 papers in corpus
other 2010
Selective blockade of prostaglandin E2 receptors EP2 and EP4 signaling inhibits proliferation of human endometriotic epithelial cells and stromal cells through distinct cell cycle arrest
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.01.038

OBJECTIVE: To determine interactions between prostaglandin (PG) E(2) signaling and proliferation of endometriotic cells to increase our knowledge about PGE(2) signaling in the pathogenesis of endometriosis in humans. DESIGN: Immortalized h…

article 2010
Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits adhesion, migration, and invasion of human endometriotic cells
·doi:10.1016/j.fertnstert.2010.07.783
article 2010
Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits invasion of human immortalized endometriotic epithelial and stromal cells through suppression of metalloproteinases
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2010.11.022

Prostaglandin E2 (PGE2) plays an important role in the pathogenesis of endometriosis. We recently reported that inhibition of COX-2 decreased migration as well as invasion of human endometriotic epithelial and stromal cells. Results of the …

article 2009
PPAR-gamma ligand activation decreases p450 aromatase gene expression in human endometriotic epithelial and stromal cells in vitro
·doi:10.1016/j.fertnstert.2009.07.046
article 2009
Selective Inhibition of Prostaglandin E2 Receptors EP2 and EP4 Induces Apoptosis of Human Endometriotic Cells through Suppression of ERK1/2, AKT, NFκB, and β-Catenin Pathways and Activation of Intrinsic Apoptotic Mechanisms
Molecular Endocrinology ·doi:10.1210/me.2009-0017

Endometriosis is a benign chronic gynecological disease of reproductive-age women characterized by the presence of functional endometrial tissues outside the uterine cavity. It is an estrogen-dependent disease. Current treatment modalities …

article 2009
Selective Inhibition of Prostaglandin E2 Receptors EP2 and EP4 Induces Apoptosis of Human Endometriotic Cells through Suppression of ERK1/2, AKT, NFκB and β-CATENIN Pathways and Activation of Intrinsic Apoptotic Mechanisms
·doi:10.1210/jcem.94.7.9993

Endometriosis is a benign chronic gynecological disease of reproductive age women characterized by the presence of functional endometrial tissues outside the uterine cavity. It is an estrogen-dependent disease. Current treatment modalities …

article 2009
Selective inhibition of prostaglandin E2 signaling inhibits migration and invasion of human endometriotic epithelial and stromal cells through multiple mechanisms
·doi:10.1016/j.fertnstert.2009.07.043
article 2008
Induction of peritoneal endometriosis in nude mice with use of human immortalized endometriosis epithelial and stromal cells: a potential experimental tool to study molecular pathogenesis of endometriosis in humans
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.06.050

ObjectiveTo determine whether a mixed population of immortalized human endometriosis epithelial and stromal cells is able to induce peritoneal endometriosis in nude mice.DesignProspective experimental study. Human immortalized endometriosis…

article 2007
Cyclooxygenase-2 Regulates Survival, Migration, and Invasion of Human Endometriotic Cells through Multiple Mechanisms
Endocrinology ·doi:10.1210/en.2007-1168

Endometriosis is a debilitating disease characterized by the presence of functional endometrial glandular epithelium and stroma outside the uterine cavity that affects up to 20% of women of child-bearing age. Cyclooxygenase-2 (COX-2), a rat…

article 2007
Gene expression profiles and functional characterization of human immortalized endometriotic epithelial and stromal cells
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.07.1358

ObjectiveTo determine whether immortalized endometriotic cells can be used as potential models to unravel pathophysiology/pathogenesis of endometriosis in humans.DesignIn vitro study. Human immortalized endometriotic epithelial and stromal …

article 2007
GENE EXPRESSION PROFILES IN HUMAN IMMORTALIZED ENDOMETRIOTIC EPITHELIAL AND STROMAL CELLS: CYCLOOXYGENASE-2 REGULATES CELL PROLIFERATION, MIGRATION AND INVASION
·doi:10.1093/biolreprod/77.s1.158

Endometriosis is a debilitating disease affects up to 20% of reproductive age women characterized by the presence of functional endometrial glandular epithelium and stroma out side the uterine cavity. The pathophysiology of endometriosis re…

article 2007
PROSTAGLANDIN E2 SIGNALING IN PATHOPHYSIOLOGY OF ENDOMETRIOSIS IN HUMAN
·doi:10.1093/biolreprod/77.s1.157b

Endometriosis is a debilitating disease affects up to 20% of reproductive age women characterized by the presence of functional endometrial glandular epithelium and stroma out side the uterine cavity. The pathophysiology of endometriosis re…