Endometriosis appears to be a systemic disease with alterations in both humoral and cell-mediated immunity. An immune defect may allow ectopic implantation of the endometrial cells with subsequent development of autoantibodies.
Both hyperprolactinemia and endometriosis are associated with infertility. A study was performed to ascertain whether sleep-related prolactin (PRL) hypersecretion was present in endometriosis. Fifty-five consecutive infertile women with reg…
The effectiveness of ovulation induction with clomiphene citrate or human menopausal gonadotropins was evaluated in 52 infertile women with stage I or stage II endometriosis and ovulatory dysfunction: anovulation or luteinized unruptured fo…
General and specific immune function were examined in women with endometriosis. Nonspecific parameters included total leukocyte and differential counts, quantitative immunoglobulin (IgG, IgA, and IgM) determinations, total hemolytic complem…
Recent investigations suggested a possible immunologic etiology for endometriosis. To determine whether cellular immunity may be affected in patients with endometriosis, peripheral lymphocyte populations were investigated in 31 confirmed en…
Endometriosis frequently presents diagnostic problems. Its symptoms and findings are non-specific and there are no non-invasive diagnostic tests. Laparoscopy is the most valuable diagnostic tool for use in a patient with endometriosis. Lapa…
Endometriosis is an enigmatic condition of unknown cause and poorly understood histogenesis. It affects women in their reproductive years limiting their fertility and seriously impairing their health. It is not entirely clear what is the me…
Danazol was administered in a daily dose of 100, 200, 400, or 600 mg for 6 months in a double-blind fashion to 27 women with pelvic endometriosis. Symptoms and pelvic findings were observed and recorded monthly. Laparoscopy and laparoscopic…
Electron microscopic examinations were carried out on 29 representative endometriotic glands obtained from 16 biopsies. Patients with endometriosis diagnosed by laparoscopy and confirmed by laparoscopic biopsy prior to hormonal treatment re…
Ninety-nine women who completed danazol treatment for endometriosis proved by operation were re-evaluated clinically an average of 37 months later. The recurrence of symptoms was reported by 39 per cent and pelvic findings suggestive of end…
Antigonadotropin (Danazol) was administered to 39 patients with endometriosis diagnosed at laparoscopy and confirmed by laparoscopic biopsy. None of the patients had surgical resection of the lesion prior to the treatment. While on the drug…