Gerard A.J. Dunselman

The chick embryo chorioallantoic membrane (CAM) bioassay was used to investigate the early pathogenesis of endometriosis. Endometrial fragments were explanted onto the CAM. The grafts including the surrounding CAM were excised at 24, 48 or …

OBJECTIVE: To assess the angiogenic activity of peritoneal fluid in women with minimal to mild endometriosis and to investigate the relationship between this activity and the concentration of macrophage-derived angiogenic factors and clinic…

OBJECTIVE: To evaluate the adhesion of endometrial fragments obtained during the proliferative phase of the menstrual cycle to fresh human peritoneum obtained during abdominal surgery. DESIGN: A prospective, descriptive, morphologic and ce…

OBJECTIVE: To study adhesion between endometrial tissue and peritoneum using intact amniotic membranes as an in vitro model. DESIGN: A cell biologic and immunohistochemical study. SETTING: Tertiary-care university medical center. PATIENT…

OBJECTIVE: Our purpose was to examine the immunohistochemical properties of epithelial cells in peritoneal fluid and to compare the staining characteristics with cells of endometrium, menstrual effluent, peritoneum, and endometriotic lesion…

OBJECTIVE: To detect the expression of integrins and E-cadherin in cells from peritoneal fluid (PF), endometrium, menstrual effluent, peritoneum, and endometriotic lesions during the early follicular phase of the menstrual cycle. DESIGN: A…

ObjectivesTo investigate whether the aminoterminal propeptides of type III procollagen are increased in patients with early endometriosis and to demonstrate that the subtle lesion of endometriosis is an active stage of the disease.DesignAmi…

STUDY OBJECTIVE: To study the isolated influence of peritoneal endometrial implants on fertility in an adhesion-free rabbit model. STUDY DESIGN: Thirty-two rabbits with endometrium implants were used; 31 rabbits with fat implants served as…