Cytoreductive surgery in ovarian carcinoma: feasibility and morbidity

A P Heintz, Heintz AP, N F Hacker, Hacker NF, Jonathan S. Berek, J S Berek, T P Rose, Rose TP, A K Munoz, Munoz AK, L D Lagasse, Lagasse LD
Obstetrics and gynecology · 1986 · doi:10.1097/00006250-198606000-00007 · PMID:3010203
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This study examined cytoreductive surgery for ovarian carcinoma, finding improved optimal cytoreduction rates with experience and that bowel resection did not increase morbidity, with stapling devices facilitating acceptable colonic reanastomosis.

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This study evaluated the feasibility and morbidity of primary cytoreductive surgery for ovarian carcinoma in 70 patients treated at the University of California, Los Angeles, between 1974 and 1984. The researchers found that optimal cytoreduction rates improved significantly from 56.4% to 87.1% as surgical experience increased over time. Common postoperative complications included fever and prolonged ileus, while bowel resection was necessary in 20% of cases without increasing overall morbidity. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Between 1974 and 1984, 70 patients underwent primary cytoreductive surgery for ovarian carcinoma at the University of California at Los Angeles. During the period of January 1974 to December 1978, optimal cytoreduction was achieved in 56.4% of the patients. With increased experience, this figure improved to 87.1% in the period of January 1979 to December 1983. The most common morbidity associated with the procedure was fever and prolonged ileus. Bowel resection was required in 20% of the patients and was not associated with increased morbidity. More liberal use of the end-to-end anastomosis stapling device facilitated low colon reanastomosis without colostomy, which contributed to the improved patient acceptance.
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Cytoreductive Surgery in Ovarian Carcinoma Feasibility and Morbidity - A. PETER M. HEINTZ - NEVILLE F. HACKER - JONATHAN S. BEREK - THANNE P. ROSE - ALAN K. MUNOZ - LEO D. LAGASSE Between 1974 and 1984, 70 patients underwent primary cytoreductive surgery for ovarian carcinoma at the University of California at Los Angeles. During the period of January 1974 to December 1978, optimal cytoreduction was achieved in 56.4% of the patients. With increased experience, this figure improved to 87.1% in the period of January 1979 to December 1983. The most common morbidity associated with the procedure was fever and prolonged ileus. Bowel resection was required in 20% of the patients and was not associated with increased morbidity. More liberal use of the end-to-end anastomosis stapling device facilitated low colon reanastomosis without colostomy, which contributed to the improved patient acceptance.(Obstet Gynecol 67:783, 1986)

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Adenocarcinoma, Mucinous Carcinoma Endometriosis Ovarian Neoplasms Adenocarcinoma Adenocarcinoma Adenocarcinoma, Mucinous Adenocarcinoma, Mucinous Aged Carcinoma Carcinoma Endometriosis Endometriosis Female Fever Fever Humans Intestinal Obstruction Intestinal Obstruction

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europepmc
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pubmed
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