Ultrasound indicator to evalutate effects of different artificial cycles of endometrial preparations on Frozen-thawed blastocyst Transfer cycles for/in patients with non-endometriosis

article OA: green CC0
AI-generated summary by qwen3.7-flash+body, 2026-09-15

In non-endometriosis patients undergoing frozen-thawed blastocyst transfer, higher 3D-power Doppler endometrial indices predicted pregnancy outcomes, whereas GnRH agonist down-regulation did not significantly improve results compared to hormone replacement therapy.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

AI-generated deep summary by qwen3.7-flash, 2026-09-15 · read from full text

This study evaluated the efficacy of simple hormone replacement therapy versus GnRH agonist down-regulation for endometrial preparation in frozen-thawed blastocyst transfer cycles among women without endometriosis. Researchers analyzed ultrasound parameters and clinical outcomes, finding no statistically significant difference in pregnancy or implantation rates between the two protocols. While higher vascular indices on Doppler ultrasound correlated with successful pregnancy, the addition of GnRH agonists did not improve results compared to standard hormone replacement alone. Relevance to endometriosis: The paper explicitly excludes patients with endometriosis from its study population to focus on non-endometriosis infertility cases.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Full text 3,854 characters · extracted from oa-html · 5 sections · click to expand

Keywords

Genitourinary, Genital / Reproductive system female, Ultrasound, Ultrasound-Colour Doppler, Ultrasound-Power Doppler, Decision analysis, Outcomes analysis, Outcomes, Prospective, Diagnostic or prognostic study, Performed at one institution Authors: W. Xiong; Chengdu/CN DOI: 10.26044/ecr2020/C-06651 Purpose Transvaginal three-dimensional ultrasonography was used to measure ultrasound parameters of simple artificial cycle and GnRH agonist down-regulation artficial cycle group on the day before transplantation in Frozen-thawed blastocyst Transfer cycles for patients with non-endometriosis。Compare the pregnancy outcomes and ultrasonic parameters of the two endometrial protocols,explore the relationship between ultrasonic parameters and pregnancy outcome,investigate the underlying factors to predict pregnancy outcome.The purpose of this study was to provide a more suitable endometrial preparation program for non-endometriosis women and a guideline for clinical evaluation of endometrial receptivity...

Methods

and materials The 120 FET cycles of non-endometriosis (non-EMT) combined infertility patients who underwent frozen-thawed embryo transfer (FET) in the assisted reproductive medicine center of Medical Sciences&Sichuan Provincial People’Hospital from January 2019 to September 2019 are the study subjects.The cycles were divided into simple artificial cycle group(hormone replacement therapy group,HRT group,n=60) and GnRH agonist down-regulation artificial cycle group(GnRH-a+HRT group,n=60).The treatment of GnRH-a was given before HRT in the cycles of GnRH-a+HRT group and the treatment was not given in the cycles of HRT group. We used transvaginal...

Results

1.The clinical pregnancy rate(75.4%) and the implantation rate(45.6%) in the GnRH-a+HRT group was higher than that in the HRT group(68.9% and 43.6%),with no statistical difference.There were no significant differences in ultrasonic indexes between two groups. 2.In the GnRH-a+HRT group and HRTgroup, there was no correlation between ultrasound parameters and pregnancy outcome.3.The relationship between ultrasound index of uterine artery and endometrial indicators and pregnancy outcomes:VI,FI and VFI of pregnant group was higher than non-pregnant group on the day before transplantation,significant difference was detected between the two...

Conclusion

1.When the non-endometriosis patients with frozen-thawed embryo selecting endometrial preparation program, GnRH agonist down-regulation artificial cycle may be NOT better than the hormone replacement treatment program.In FET patients, female AMH and the number of embryos transferred are independent factors of clinical pregnancy.3.it is more likely to get pregnancy,When endometrial index of 3D-power Doppler ultrasound are higher.VI,FI and VFI are better indicator to predictor outcome of thaw frozen blastocyst transfer cycles.4.Uterine artery and endometrial blood flow parameters have no significant difference between different artificial cycles to...

References

[1]Ombelet W. Is global access to infertility care realistic? The Walking Egg Project.[J]. Reproductive Biomedicine Online, 2014, 28(3):267-272. [2]Cohen J, Simons R F, Fehilly C B, et al. Birth after replacement of hatching blastocyst cryopreserved at expanded blastocyst stage.[J]. Lancet, 1985, 325(8429):647-647. [3]Rashid NA, Lalitkumar S,Lalitkumar PG,et al. Endometrial receptivity and human embryo implantation [J]. Am J Reprod Immunol, 2011, 66(1): 23-30. [4]Groenewoud E R , Cantineau A E P , Kollen B J , et al. What is the optimal means of preparing the...

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-html

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosis

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

openalex
last seen: 2026-05-10T10:43:52.478320+00:00
License: CC0 · commercial use OK