{"paper_id":"ff7d5db1-d489-4230-82bb-24e74febf0b7","body_text":"ECR 2020 / C-06651\nUltrasound indicator to evalutate effects of different artificial cycles of endometrial preparations on Frozen-thawed blastocyst Transfer cycles for/in patients with non-endometriosis\nCongress:\nECR 2020\nPoster Number:\nC-06651\nType:\nScientific Exhibit\nKeywords:\nGenitourinary, Genital / Reproductive system female, Ultrasound, Ultrasound-Colour Doppler, Ultrasound-Power Doppler, Decision analysis, Outcomes analysis, Outcomes, Prospective, Diagnostic or prognostic study, Performed at one institution\nAuthors:\nW. Xiong; Chengdu/CN\nDOI:\n10.26044/ecr2020/C-06651\nPurpose\nTransvaginal three-dimensional ultrasonography was used to measure ultrasound parameters of simple artificial cycle and GnRH agonist down-regulation artficial cycle group on the day before transplantation in Frozen-thawed blastocyst Transfer cycles for patients with non-endometriosis。Compare the pregnancy outcomes and ultrasonic parameters of the two endometrial protocols,explore the relationship between ultrasonic parameters and pregnancy outcome,investigate the underlying factors to predict pregnancy outcome.The purpose of this study was to provide a more suitable endometrial preparation program for non-endometriosis women and a guideline for clinical evaluation of endometrial receptivity...\nMethods and materials\nThe 120 FET cycles of non-endometriosis (non-EMT) combined infertility patients who underwent frozen-thawed embryo transfer (FET) in the assisted reproductive medicine center of Medical Sciences&Sichuan Provincial People’Hospital from January 2019 to September 2019 are the study subjects.The cycles were divided into simple artificial cycle group(hormone replacement therapy group，HRT group，n=60) and GnRH agonist down-regulation artificial cycle group(GnRH-a+HRT group,n=60).The treatment of GnRH-a was given before HRT in the cycles of GnRH-a+HRT group and the treatment was not given in the cycles of HRT group. We used transvaginal...\nResults\n1.The clinical pregnancy rate(75.4%) and the implantation rate(45.6%) in the GnRH-a+HRT group was higher than that in the HRT group(68.9% and 43.6%),with no statistical difference.There were no significant differences in ultrasonic indexes between two groups.\n2.In the GnRH-a+HRT group and HRTgroup, there was no correlation between ultrasound parameters and pregnancy outcome.3.The relationship between ultrasound index of uterine artery\nand endometrial indicators and pregnancy outcomes：VI,FI and VFI of pregnant group was higher than non-pregnant group on the day before transplantation,significant difference was detected between the two...\nConclusion\n1.When the non-endometriosis patients with frozen-thawed embryo selecting endometrial preparation program, GnRH agonist down-regulation artificial cycle may be NOT better than the hormone replacement treatment program.In FET patients, female AMH and the number of embryos transferred are independent factors of clinical pregnancy.3．it is more likely to get pregnancy，When endometrial index of 3D-power Doppler ultrasound are higher．VI，FI and VFI are better indicator to predictor outcome of thaw frozen blastocyst transfer cycles.4.Uterine artery and endometrial blood flow parameters have no significant difference between different artificial cycles to...\nReferences\n[1]Ombelet W. Is global access to infertility care realistic? The Walking Egg Project.[J]. Reproductive Biomedicine Online, 2014, 28(3):267-272.\n[2]Cohen J, Simons R F, Fehilly C B, et al. Birth after replacement of hatching blastocyst cryopreserved at expanded blastocyst stage.[J]. Lancet, 1985, 325(8429):647-647.\n[3]Rashid NA, Lalitkumar S,Lalitkumar PG,et al. Endometrial receptivity and human embryo implantation [J]. Am J Reprod Immunol, 2011, 66(1)： 23-30.\n[4]Groenewoud E R , Cantineau A E P , Kollen B J , et al. What is the optimal means of preparing the...","source_license":"CC0","license_restricted":false}