Additional file 8 of Single-cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis

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Analysis of uterine NK cell subclusters identified a proliferative subset, uNK2, enriched in control endometrial tissues and characterized by high expression of MKI67 and TOP2A.

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Abstract

Additional file 8. uNK subclusters reveal a proliferating uNK subcluster enriched in control ME. We have examined subclusters of uterine NK (uNK) cells in our dataset and identified a subcluster whose gene expression patterns reflect cell proliferation, with substantial enrichment of MKI67 and TOP2A. This subset is over 98% matched to a proliferative uNK cell subcluster defined in the decidua of first trimester pregnancy [26]. This subset corresponds to our subset uNK2 that is enriched in controls (Fig. 3).

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endometriosis

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last seen: 2026-05-11T08:51:17.274897+00:00
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