MEDICAL MANAGEMENT OF LEIOMYOMATA AND SUSPECTED ENDOMETRIOSIS IN AN ALLEN'S SWAMP MONKEY (ALLENOPITHECUS NIGROVIRIDUS)

Yousuf S. Jafarey, Jafarey YS, Hanley CS, Christopher S. Hanley, Ric A. Berlinski, Berlinski RA, Connie Warner, Warner C, A. Robert Armstrong, Armstrong A, Anthony Armstrong
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians · 2015 · vol. 46(4) , pp. 913–917 · doi:10.1638/2014-0224.1 · PMID:26667550 · W2200225198
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Leuprolide acetate treatment reduced uterine leiomyomata and ovarian activity in a swamp monkey with suspected endometriosis, and a deslorelin implant provided sustained remission of bleeding.

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Abstract

A 13-yr-old female nulliparous Allen's swamp monkey (Allenopitchecus nigroviridis) presented with intermittent excessive vaginal bleeding, cyclical lethargy, and a history of irregular menstrual cycles. Abdominal ultrasonography revealed a subjectively thickened, irregular endometrium, multiple leiomyomata (uterine fibroids), and bilateral anechoic foci on the ovaries. Treatment was initiated with leuprolide acetate i.m. monthly for 6 mo. Recheck ultrasound at 3 mo showed a decrease in leiomyoma diameter and no evidence of active follicles on the ovaries. Eleven months following completion of treatment, clinical signs recurred and the animal was treated with a deslorelin implant. Since implant placement, no vaginal bleeding has been noted.

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Condition tags

endometriosis

MeSH descriptors

Cercopithecinae Cercopithecinae Endometriosis Leiomyoma Monkey Diseases Animals Animals Antineoplastic Agents, Hormonal Antineoplastic Agents, Hormonal Antineoplastic Agents, Hormonal Drug Implants Drug Implants Endometriosis Endometriosis Enzyme Inhibitors Enzyme Inhibitors Enzyme Inhibitors Enzyme Inhibitors Female Female

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