Clinical status of reproductive aged women with combined pathology of the uterus – leiomyoma and adenomyosis

М. Б. Запорожченко, А. В. Сидоренко, Д. Ю. Парубина
In: Reproductive Endocrinology · 2019 · vol. 0(50) , pp. 51–55 · doi:10.18370/2309-4117.2019.50.51-55 · W2997558734
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This study examined 120 reproductive-aged women with combined uterine leiomyoma and adenomyosis, finding 100% had extragenital pathologies and complex metabolic disorders affecting disease course.

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Abstract

Clinical assessment of the general status of patients with combined uterine pathology (leiomyoma (LM) and adenomyosis) has a practical importance for determining specific therapeutic tactics. The study of the general condition of reproductive aged women with this pathology allows determining of many factors that can affect the clinical course of disease.Purpose of the study was to investigate the clinical status of reproductive aged women who suffer from combined uterine pathology – LM and adenomyosis.Materials and methods. 120 women of reproductive age were examined. Group IA united 60 patients with combined uterine pathology – asymptomatic LM and nodal, diffuse, diffuse-focal adenomyosis III, IV degrees of severity with active clinical course; group IB united 60 patients with combined uterine pathology - symptomatic LM and diffuse, diffuse focal adenomyosis I, II degrees of severity with inactive clinical course. Examination was carried out in accordance with the orders of the Ministry of Health of Ukraine.Results. A study of the general status of reproductive aged women has revealed many factors that can affect the clinical course of disease. The study of nosological forms of extragenital pathology revealed a wide range of different organs and systems diseases, co-morbidities of mainly chronic course, varying severity in 100% of women. A number of somatic diseases can be both a cause and a consequence of gynecological pathology, especially hormonal etiology. Analysis of the anamnestic data on the transferred gynecological diseases showed 100% frequency of the combined and concomitant pathology of the female genital tract.Conclusions. Completed study involving reproductive aged women with combined uterine pathology (LM and adenomyosis) showed many factors that can affect the clinical course of disease. Obtained data indicate that there are complex metabolic disorders in the women’s body suffering from that combined uterine pathology.

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adenomyosis

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