Clinical status of reproductive aged women with combined pathology of the uterus – leiomyoma and adenomyosis
This study examined 120 reproductive-aged women with combined uterine leiomyoma and adenomyosis, finding 100% had extragenital pathologies and complex metabolic disorders affecting disease course.
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This paper investigated the clinical status of 120 reproductive-aged women with combined uterine pathology consisting of uterine leiomyoma and adenomyosis, stratifying them into two groups: one with asymptomatic leiomyoma and higher-severity, actively symptomatic adenomyosis (group IA) and another with symptomatic leiomyoma and lower-severity adenomyosis with inactive clinical course (group IB). Using clinical assessment per Ukrainian Ministry of Health orders, the authors found that all women had comorbidities of mainly chronic course across a wide range of extragenital organs and systems, and that anamnestic data showed 100% frequency of combined and concomitant pathology of the female genital tract. They concluded that multiple factors, including complex metabolic disorders, may influence disease course, while explicitly limiting the work to describing clinical status rather than establishing causal mechanisms. This paper is centrally about endometriosis and/or adenomyosis — it focuses on adenomyosis combined with uterine leiomyoma and characterizes the clinical status and comorbidity patterns in affected reproductive-aged women.
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References (19)
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- New approaches to the treatment of endometriosis via openalex
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