Primary vesical clear cell adenocarcinoma arising in endometriosis: a rare case of mullerian origin.

Anticancer research · 2013 · vol. 33(2) , pp. 615–7 · PMID:23393356 · W2102540188
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This case review presents a 59-year-old patient treated for clear cell adenocarcinoma arising from bladder endometriosis, discussing its histogenesis and current WHO classification.

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Abstract

Clear cell adenocarcinoma arising out of endometriosis of the urinary bladder is a rare entity. The published literature has a dearth of information about this entity and its histogenesis. In the present case review we present a 59-year-old patient who was treated with robotic anterior pelvic exenteration and ileal conduit. The initial biopsy of bladder tumour purported a high-grade urothelial carcinoma, however the final specimen revealed a clear cell adenocarcinoma arising in endometriosis without any urothelial cancer. Early case reports refer to these lesions as mesonephric or mesonephroid adenocarcinomas but the current WHO nomenclature classifies them under non-urothelial epithelial neoplasms as clear cell adenocarcinomas. Here, we review the literature and discuss their origins.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Endometriosis Endometriosis Urinary Bladder Neoplasms Urinary Bladder Neoplasms Adenocarcinoma, Clear Cell Endometriosis Female Humans Middle Aged Urinary Bladder Neoplasms

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