Androgen, estrogen and progestin binding in cytosols of benign gynecologic tumors and tumor-like lesions

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Abstract

Specific androgen (Kd 0.27 +/- 0.06 nM), estrogen (Kd 0.19 +/- 0.04 nM) and progestin (Kd 0.22 +/- 0.07 nM) binding were investigated in benign gynecologic tumors and tumor-like lesions. The simultaneous presence of androgen and progestin receptors was a common finding. In one endometrioma, specific androgen, estrogen and progestin binding was observed simultaneously.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Ovarian Neoplasms Receptors, Androgen Receptors, Estrogen Receptors, Progesterone Adult Aged Cystadenoma Cystadenoma Cytosol Cytosol Dysgerminoma Dysgerminoma Endometriosis Endometriosis Female Humans Middle Aged Ovarian Cysts Ovarian Cysts Ovarian Neoplasms

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europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
pubmed
last seen: 2026-05-13T22:09:40.384591+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine