Adnexal Endometriosis. Typical Benign Endometriosis

In: Imaging of Endometriosis: A Comparative Guide of US, MRI and Surgery · 2025 · pp. 41–66 · doi:10.1007/978-3-031-82750-1_3 · W4410897568
book-chapter OA: closed CC0
Full text JSON View on OpenAlex View at publisher
AI-generated summary by claude@2026-06+body, 2026-06-08

Transvaginal and transabdominal ultrasound provide information about adnexal endometriosis, while MRI is the modality of choice for staging, using signs like T2 shading, rim sign, and T2 dark spot sign.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text

This paper examines imaging approaches for adnexal endometriosis, focusing on how transvaginal/transabdominal ultrasound and especially MRI can identify and stage ovarian/endometrial changes using signs such as T2 shading, the rim sign, and the T2 dark spot sign. It highlights that these MRI features reflect blood product behavior and therefore may also appear in hemorrhagic cysts, limiting diagnostic specificity, and notes ongoing debate about whether surgical decisions before IVF affect ovarian reserve versus the endometriosis itself. The chapter discusses potential challenges for IVF procedures involving adnexal lesions and mentions that pregnancy-related hormones could have therapeutic effects in some cases. Relevance to endometriosis: the paper is directly about adnexal endometriosis imaging and explicitly uses endometriosis/ovarian endometrioma features (e.g., T2 dark spot sign) to differentiate from hemorrhagic cysts, which is central to endometriosis and thereby also relevant in the broader endometriosis/adenomyosis corpus.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Full text 8,767 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Abstract

Endometriosis is a complex disease with different degrees of expression. Although using ultrasound (US) with the transvaginal and transabdominal approaches yields a lot of information, especially about adnexal endometriosis, magnetic resonance (MR) is the modality of choice to see its exact stage. Several signs are not absolutely pathognomic but have high sensitivity and specificity in identifying endometrial ovarian changes. T2 shading sign (dropping signal intensity on T2) was for 2 decades thought as the most important technique until complete and incomplete rim sign and T2 dark spot sign were also established to help in reaching diagnoses. As all these signs are based on the behavior of blood products, they can be found in hemorrhagic cysts as well. Active debate persists about surgery indications for patients who are in the program of in vitro fertilization (IVF) and the influence of endometriosis per se versus surgery on the ovarian reserve. Although some potential difficulties might be encountered during aspiration and other manipulations during IVF, the influence of hormones during pregnancy could have even a therapeutic effect in some cases. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

References

Smolarz B, Szyłło K, Romanowicz H. Endometriosis: epidemiology, classification, pathogenesis, treatment and genetics (review of literature). Int J Mol Sci. 2021;22(19):10554. https://doi.org/10.3390/ijms221910554. PMID: 34638893; PMCID: PMC8508982. Chamié LP, Blasbalg R, Pereira RM, Warmbrand G, Serafini PC. Findings of pelvic endometriosis at transvaginal US, MR imaging, and laparoscopy. Radiographics. 2011;31(4):E77–100. https://doi.org/10.1148/rg.314105193. Viala-Trentini M, Maubon A, Filhastre M, Georges P, Rouanet J-P. Imagerie de l’hypofertilité de la femme. EMC Encyclopédie Médico-Chirurgicale (Elsevier SAS, Paris; 2006), Radiodiagnostic—Urologie-Gynécologie, 34–620-E-10. Hsu AL, Khachikyan I, Stratton P. Invasive and noninvasive methods for the diagnosis of endometriosis. Clin Obstet Gynecol. 2010;53(2):413–9. https://doi.org/10.1097/GRF.0b013e3181db7ce8. Outwater EK, Siegelman ES, Chiowanich P, et al. Dilated fallopian tubes: MR imaging characteristics. Radiology. 1998;208:463–9. https://doi.org/10.1148/radiology.208.2.9680577. Foti PV, Ognibene N, Spadola S, et al. Non-neoplastic diseases of the fallopian tube: MR imaging with emphasis on diffusion-weighted imaging. Insights Imaging. 2016;7:311–27. https://doi.org/10.1007/s13244-016-0484-7. Nisenblat V, Bossuyt PM, Farquhar C, Johnson N, Hull ML. Imaging modalities for the non-invasive diagnosis of endometriosis. Cochrane Database Syst Rev. 2016;2:CD009591. Medeiros LR, Rosa MI, Silva BR, et al. Accuracy of magnetic resonance in deeply infiltrating endometriosis: a systematic review and meta-analysis. Arch Gynecol Obstet. 2015;291:611–21. https://doi.org/10.1007/s00404-014-3470-7. Corwin MT, Gerscovich EO, Lamba R, Wilson M, McGahan JP. Differentiation of ovarian endometriomas from hemorrhagic cysts at MR imaging: utility of the T2 dark spot sign. Radiology. 2014;271:126–32. Bazot M, Lafont C, Rouzier R, Roseau G, Thomassin-Naggara I, Daraï E. Diagnostic accuracy of physical examination, transvaginal sonography, rectal endoscopic sonography, and magnetic resonance imaging to diagnose deep infiltrating endometriosis. Fertil Steril. 2009;92:1825–33. Sampson JA. Peritoneal endometriosis due to menstrual dissemination of endometrial tissue into the peritoneal cavity. Am J Obstet Gynecol. 1927;14:422–69. Bazot M, Bharwani N, Huchon C, Kinkel K, Cunha TM, Guerra A, et al. European society of urogenital radiology (ESUR) guidelines: MR imaging of pelvic endometriosis. Eur Radiol. 2017;27:2765–75. Togashi K, Nishimura K, Kimura I, Tsuda Y, Yamashita K, Shibata T, et al. Endometrial cysts: diagnosis with MR imaging. Radiology. 1991;180:73–8. Jeong Y-Y, Outwater EK, Kang HK. Imaging evaluation of ovarian masses. Radiographics. 2000;20:1445–70. https://doi.org/10.1148/radiographics.20.5.g00se101445. Coutinho A Jr, Bittencourt LK, Pires CE, et al. MR imaging in deep pelvic endometriosis: a pictorial essay. Radiographics. 2011;31(2):549–67. https://doi.org/10.1148/rg.312105144. Woodward PJ, Sohaey R, TP M Jr. Endometriosis: radiologic-pathologic correlation. Radiographics. 2001;21(1):193–216. https://doi.org/10.1148/radiographics.21.1.g01ja14193. Redwine DB. Diaphragmatic endometriosis: diagnosis, surgical management, and long-term results of treatment. Fertil Steril. 2002;77:288–96. https://doi.org/10.1016/S0015-0282(01)02998-3. Mannan K, Altaf F, Maniar S, Tirabosco R, Sinisi M, Carlstedt T. Cyclical sciatica: endometriosis of the sciatic nerve. J Bone Joint Surg Br. 2008;90(1):98–101. https://doi.org/10.1302/0301-620X.90B1.19832. Tham WP, Busmanis I, Tan WC, Kwek JW. Polypoid endometriosis of post vaginal fornix: utility of MRI imaging of pelvis with diffusion weighted imaging for diagnosis. Med J Malaysia. 2016;71(3):144–6. Pham M, Sommer C, Wessig C, et al. Magnetic resonance neurography for the diagnosis of extrapelvic sciatic endometriosis. Fertil Steril. 2010;94(1):351.e11–4. https://doi.org/10.1016/j.fertnstert.2009.12.046. Di Paola V, Manfredi R, Castelli F, Negrelli R, Mehrabi S, Pozzi MR. Detection and localization of deep endometriosis by means of MRI and correlation with the ENZIAN score. Eur J Radiol. 2015;84(4):568–74. https://doi.org/10.1016/j.ejrad.2014.12.017. Takeuchi M, Matsuzaki K, Nishitani H. Susceptibility-weighted MRI of endometrioma: preliminary results. AJR Am J Roentgenol. 2008;191(5):1366–70. https://doi.org/10.2214/AJR.07.3974. AbedTwfeq RH, Jawad NS. Differentiation between ovarian endometriotic cysts and functional hemorrhagic cysts on magnetic resonance imaging. Iraqi Postgrad Med J. 2021;20(4):361. Foti PV, Attinà G, Spadola S, et al. MR imaging of ovarian masses: classification and differential diagnosis. Insights Imaging. 2016;7(1):21–41. https://doi.org/10.1007/s13244-015-0455-4. Dunselman GA, Vermeulen N, Becker C, Calhaz-Jorge C, D’Hooghe T, De Bie B, et al. ESHRE guideline: management of women with endometriosis. Hum Reprod. 2014;29:400–12. Practice Committee of the American Society for Reproductive Medicine. Endometriosis and infertility. Fertil Steril. 2004;82:40–5. Nisolle M, Donnez J. Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities. Fertil Steril. 1997;68:585–96. Barnhart K, Dunsmoor-Su R, Coutifaris C. Effect of endometriosis on in vitro fertilization. Fertil Steril. 2002;77(6):1148–55. Somigliana E, Benaglia L, Vighi V, Ragni G, Vercellini P, Fedele L. Rate of severe ovarian damage following surgery for endometriomas. Hum Reprod. 2010;25(3):678–82. Benaglia L, Somigliana E, Vercellini P, Abbiati A, Ragni G, Fedele L. Endometriotic ovarian cysts negatively affect the rate of spontaneous ovulation. Hum Reprod. 2009;24(9):2183–6. Bongioanni F, Revelli A, Gennarelli G, Guidetti D, Delle Piane LD, Holte J. Ovarian endometriomas and IVF: a retrospective case-control study. Reprod Biol Endocrinol. 2011;9:81. Vercellini P, Crosignani PG, Abbiati A, Somigliana E, Vigano P, Fedele L. The effect of surgery for symptomatic endometriosis: the other side of the story. Hum Reprod Update. 2009;15(2):177–88. Kennedy S, Bergqvist A, Chapron C, D’Hooghe T, Dunselman G, Saridogan E, et al. ESHRE guideline on the diagnosis and management of endometriosis. Hum Reprod. 2005;20(10):2698–704. Benschop L, Farquhar C, van der Poel N, Heineman MJ. Interventions for women with endometrioma prior to assisted reproductive technology. Cochrane Database Syst Rev. 2010;10(11):CD008571. Charkhchi P, Butcher M, Macura KJ. Vanishing pelvic mass: decidualized endometriosis during pregnancy. Radiol Case Rep. 2024;19(6):2535–9. https://doi.org/10.1016/j.radcr.2024.03.018. PMID: 38585388; PMCID: PMC10997803. Author information Authors and Affiliations Corresponding author Editor information Editors and Affiliations Rights and permissions Copyright information © 2025 The Author(s), under exclusive license to Springer Nature Switzerland AG About this chapter Cite this chapter Stojanović, S., Kopitović, V., Anđelić, L., Milatović, S., Molnar, U. (2025). Adnexal Endometriosis. Typical Benign Endometriosis. In: Thomassin-Naggara, I. (eds) Imaging of Endometriosis: A Comparative Guide of US, MRI and Surgery. Springer, Cham. https://doi.org/10.1007/978-3-031-82750-1_3 Download citation DOI: https://doi.org/10.1007/978-3-031-82750-1_3 Published: Publisher Name: Springer, Cham Print ISBN: 978-3-031-82749-5 Online ISBN: 978-3-031-82750-1 eBook Packages: MedicineMedicine (R0)

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Outcome instruments

Enzian

Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (33)

Source provenance

openalex
last seen: 2026-06-04T00:00:01.174412+00:00
License: CC0 · commercial use OK