Intravesical lignocaine in the diagnosis of bladder pain syndrome
Intravesical lignocaine instillation reduced pain in 68% of women with pelvic pain, aiding in the exclusion of non-bladder origins for their pain.
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This study evaluated whether intravesical instillation of 2% lignocaine could help distinguish pain originating from the urinary bladder versus other pelvic organs in 22 women with pelvic pain, using visual analogue scale (VAS) ratings before and at 2, 10, and 20 minutes after instillation. A 50% reduction in VAS defined responders, who then underwent cystoscopy under anaesthesia; 15 of 22 women (68.18%) were responders, and 13 of these 15 had cystoscopic features suggestive of bladder pain syndrome/interstitial cystitis. Among the seven non-responders, two were diagnosed with endometriosis, four with pelvic inflammatory disease, and one with diverticulitis. The paper relates to endometriosis because endometriosis was specifically identified in two non-responders who did not show pain reduction after intravesical lignocaine, though the study’s main focus is diagnostic exclusion of non-bladder sources of bladder-region pelvic pain.
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- Current issues in the diagnosis of painful bladder syndrome/interstitial cystitis. via openalex
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