{"paper_id":"eee3ff00-9e1c-4e71-b2c2-b8ac9276e327","body_text":"Abstract\nIntroduction and hypothesis\nTo differentiate between the pain originating from urinary bladder and that due to other pelvic organs, using intravesical instillations of 2% lignocaine solution.\nMethods\nTwenty-two women with pelvic pain received intravesical instillation of 20 ml of 2% lignocaine solution. The intensity of pain was recorded by using visual analogue scale (VAS) just before, at 2, 10 and 20 min after intravesical instillation. Women who experienced a drop in the VAS score by 50% were termed as responders. All these women underwent cystoscopy under anaesthesia.\nResults\nFifteen out of 22 (68.18%) women experienced a substantial reduction in the pain. Thirteen out of these 15 women had features suggestive of BPS/IC on cystoscopy. Out of the seven non-responders, two women were found to have endometriosis, four were diagnosed as pelvic inflammatory disease and one had diverticulitis.\nConclusions\nIntravesical lignocaine appears to be useful in excluding patients with pelvic pain originating from organs other than the urinary bladder.\nSimilar content being viewed by others\nAbbreviations\n- BPS:\n-\nBladder pain syndrome\n- IC:\n-\nInterstitial cystitis\n- VAS:\n-\nVisual analogue scale\nReferences\nParsons CL (2004) Diagnosing chronic pelvic pain of bladder origin. J Reprod Med 49(3 Suppl):235–242\nEvans RJ, Stanford EJ (2006) Current issues in the diagnosis of painful bladder syndrome/interstitial cystitis. J Reprod Med 51(3 Suppl):241–252\nAsklin B, Cassuto J (1989) Intravesical lidocaine in severe interstitial cystitis. Scand J Urol Nephrol 23(4):311–312\nParsons CL (2005) Successful down regulation of bladder sensory nerves with combination of heparin and alkalinized lidocaine in patients with interstitial cystitis. Urology 65:45–48\nTaneja R, Jawade KK (2007) Rational combination of intravesical and systemic agents for the treatment of interstitial cystitis. Scand J Urol Nephrol 41(6):511–515\nIbrahim IA, Diokno AC, Killinger KA et al (2007) Prevalence of self-reported interstitial cystitis (IC) and interstitial-cystitis-like symptoms among adult women in the community. Int Urol Nephrol 39(2):489–495\nKushner L, Moldwin RM (2006) Efficiency of questionnaires used to screen for interstitial cystitis. J Urol 176(2):587–592\nGiannakopoulos X, Champilomatos P (1992) Chronic interstitial cystitis: successful treatment with intravesical lidocaine. Arch Ital Urol Nefrol Androl 64:337–339\nSeth A, Teichmann JMH (2008) What's new in the diagnosis and management of painful bladder syndrome/interstitial cystitis. Curr Urol Rep 9:349–357\nHenry R, Patterson L, Avery N et al (2001) Absorption of alkalized intravesical lidocaine in normal and inflamed bladders: a simple method for improving bladder anesthesia. J Urol 165:1900–1903\nOh SJ, Paick SH, Lim DJ et al (2005) Effects of local anesthetics on human bladder contractility. Neurourol Urodyn 24(3):288–294\nWewers ME, Lowe NK (1990) A critical review of visual analogue scales in the measurement of clinical phenomena. Res Nurs Health 13:227–236\nAcknowledgements\nI thank Mr. Madan Gopal Chouhan, Ms. Parbati Nayak and Ms. Rajbir Kaur for their cooperation and earnest effort during the course of this study.\nConflicts of interest\nNone.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nRights and permissions\nAbout this article\nCite this article\nTaneja, R. Intravesical lignocaine in the diagnosis of bladder pain syndrome. Int Urogynecol J 21, 321–324 (2010). https://doi.org/10.1007/s00192-009-1045-0\nReceived:\nAccepted:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s00192-009-1045-0","source_license":"CC0","license_restricted":false}