Abstract
Cesarean delivery is a common procedure, currently accounting for one-third of live births in the US. In the acute post-operative setting, it can be difficult to distinguish changes of the expected recovery of the uterus from those of complications. A radiologist should be able to recognize expected postoperative findings and their evolution, such as endometrial cavity debris, small hematoma, or peri-incisional edema, when interpreting images at various stages of recovery. Commonly seen acute complications after cesarean delivery include subfascial and bladder flap hematomas, uterine dehiscence or rupture, endometritis, septic thrombophlebitis, retained products of conception, and vascular complications such as uterine artery pseudoaneurysm, arteriovenous fistula, and ovarian vein thrombosis. On the contrary, delayed complications include uterine scar niche, cesarean scar ectopic pregnancy, endometriosis, pelvic inflammatory disease, bowel obstruction, that occur beyond the post-partum period and are often manifested during subsequent pregnancies. This review aims to familiarize radiologists with the pathophysiology and timeline of the expected post-cesarean imaging findings and complications, to aid accurate diagnosis and prompt patient management.
Graphical abstract
Data availability
No datasets were generated or analysed during the current study.
References
Betran AP, Ye J, Moller AB, Souza JP, Zhang J (2021) Trends and projections of caesarean section rates: global and regional estimates. BMJ Glob Health. https://doi.org/10.1136/bmjgh-2021-005671
Osterman MJK, Hamilton BE, Martin JA, Driscoll AK, Valenzuela CP. Births: Final Data for 2021. In: Services Usdohah, ed. Hyattsville, MD: National Center for Health Statistics, 2023.
Hager RM, Daltveit AK, Hofoss D, Nilsen ST, Kolaas T, Oian P, Henriksen T. Complications of cesarean deliveries: rates and risk factors. Am J Obstet Gynecol 2004;190(2):428–434. doi: https://doi.org/10.1016/j.ajog.2003.08.037
Murphy DJ (2023) Clinical Obstetrics and Gynaecology: Clinical Obstetrics and Gynaecology, 5th edn. Elsevier, pp 435–445
Gonzalo-Carballes M, Ríos-Vives M, Fierro EC, Azogue XG, Herrero SG, Rodríguez AE, Rus MN, Planes-Conangla M, Escudero-Fernandez JM, Coscojuela P (2020) A pictorial review of postpartum complications. Radiographics 40(7):2117–2141. https://doi.org/10.1148/rg.2020200031
Al-Muzrakchi A, Jawad N, Crofton M, Ahmed S, Dick E, Gedroyc W, Bharwani N. Imaging in the post-partum period: clinical challenges, normal findings, and common imaging pitfalls. Abdom Radiol (NY) 2017;42(5):1543–1555. doi: https://doi.org/10.1007/s00261-017-1090-y
Wang SS, Shum D, Kennedy A. Imaging of Postpartum/Peripartum Complications. Radiol Clin North Am 2020;58(2):431–443. doi: https://doi.org/10.1016/j.rcl.2019.10.007
Matsumoto MM, Caridi TM. Uterine Vascular Anomalies: Management and Treatment Overview. Semin Intervent Radiol 2023;40(4):342–348. doi: https://doi.org/10.1055/s-0043-1770714
Rosa F, Perugin G, Schettini D, Romano N, Romeo S, Podestà R, Guastavino A, Casaleggio A, Gandolfo N. Imaging findings of cesarean delivery complications: cesarean scar disease and much more. Insights Imaging 2019;10(1):98. doi: https://doi.org/10.1186/s13244-019-0780-0
Rodgers SK, Kirby CL, Smith RJ, Horrow MM. Imaging after cesarean delivery: acute and chronic complications. Radiographics 2012;32(6):1693–1712. doi: https://doi.org/10.1148/rg.326125516
Aran S, Daftari Besheli L, Karcaaltincaba M, Gupta R, Flores EJ, Abujudeh HH. Applications of dual-energy CT in emergency radiology. AJR Am J Roentgenol 2014;202(4):W314-324. doi: https://doi.org/10.2214/ajr.13.11682
Sierra A, Burrel M, Sebastia C, Radosevic A, Barrufet M, Albela S, Buñesch L, Domingo MA, Salvador R, Real I. Utility of multidetector CT in severe postpartum hemorrhage. Radiographics 2012;32(5):1463–1481. doi: https://doi.org/10.1148/rg.325115113
Bekiesinska-Figatowska M. Magnetic resonance imaging of the female pelvis after Cesarean section: a pictorial review. Insights Imaging 2020;11(1):75. doi: https://doi.org/10.1186/s13244-020-00876-5
Moshiri M, Osman S, Bhargava P, Maximin S, Robinson TJ, Katz DS. Imaging evaluation of maternal complications associated with repeat cesarean deliveries. Radiol Clin North Am 2014;52(5):1117–1135. doi: https://doi.org/10.1016/j.rcl.2014.05.010
Aboughalia H, Basavalingu D, Revzin MV, Sienas LE, Katz DS, Moshiri M. Imaging evaluation of uterine perforation and rupture. Abdom Radiol (NY) 2021;46(10):4946–4966. doi: https://doi.org/10.1007/s00261-021-03171-z
Rezvani M, Shaaban AM, Kennedy AM. The role of multimodality imaging after cesarean delivery. Ultrasound Q 2015;31(1):5–18. doi: https://doi.org/10.1097/ruq.0000000000000075
Wu T, Lin B, Li K, Ye J, Wu R. Diagnosis and treatment of uterine artery pseudoaneurysm: Case series and literature review. Medicine (Baltimore) 2021;100(51):e28093. doi: https://doi.org/10.1097/md.0000000000028093
Lo TS, Wijaya T, Lo LM, Kao CC, Wu PY, Cortes EF, Huang SY, Lin CH. Clinical Relevance and Treatment Selection of Ureteral Injury After Cesarean Section. Female Pelvic Med Reconstr Surg 2016;22(5):303–306. doi: https://doi.org/10.1097/spv.0000000000000275
Ahmed HA, Bu Shurbak ZS, Babarinsa IA, Hussain Saleh HA, Khenyab N, Ahmed Z, Minisha F (2022) Small bowel injury during peritoneal entry at cesarean section: a five-year case series. Cureus 14(11):e31072. https://doi.org/10.7759/cureus.31072
Ustunsoz B, Ugurel S, Duru NK, Ozgok Y, Ustunsoz A. Percutaneous management of ureteral injuries that are diagnosed late after cesarean section. Korean J Radiol 2008;9(4):348–353. doi: https://doi.org/10.3348/kjr.2008.9.4.348
Jonard M, Ducloy-Bouthors AS, Boyle E, Aucourt M, Gasan G, Jourdain M, Mignaux V, Tillouche N, Fourrier F. Postpartum acute renal failure: a multicenter study of risk factors in patients admitted to ICU. Ann Intensive Care 2014;4:36. doi: https://doi.org/10.1186/s13613-014-0036-6
Kim J, Choi JH, Shin BS, Nam JY, Kang EA, Kim JS, Hwang JH, Kim J. A Case of Idiopathic Severe Acute Pancreatitis following Cesarean Section Delivery. Korean J Gastroenterol 2016;68(3):161–165. doi: https://doi.org/10.4166/kjg.2016.68.3.161
Budny-Winska J, Pomorski M. Uterine niche after cesarean section: a review of diagnostic methods. Ginekol Pol 2021;92(10):726–730. doi: https://doi.org/10.5603/GP.a2021.0195
Armstrong F, Mulligan K, Dermott RM, Bartels HC, Carroll S, Robson M, Corcoran S, Parland PM, Brien DO, Brophy D, Brennan DJ. Cesarean scar niche: An evolving concern in clinical practice. Int J Gynaecol Obstet 2023;161(2):356–366. doi: https://doi.org/10.1002/ijgo.14509
Tanos V, Toney ZA. Uterine scar rupture - Prediction, prevention, diagnosis, and management. Best Pract Res Clin Obstet Gynaecol 2019;59:115–131. doi: https://doi.org/10.1016/j.bpobgyn.2019.01.009
Kok N, Wiersma IC, Opmeer BC, de Graaf IM, Mol BW, Pajkrt E. Sonographic measurement of lower uterine segment thickness to predict uterine rupture during a trial of labor in women with previous Cesarean section: a meta-analysis. Ultrasound Obstet Gynecol 2013;42(2):132–139. doi: https://doi.org/10.1002/uog.12479
Alamo L, Vial Y, Denys A, Andreisek G, Meuwly JY, Schmidt S. MRI findings of complications related to previous uterine scars. Eur J Radiol Open 2018;5:6–15. doi: https://doi.org/10.1016/j.ejro.2018.01.001
Whittington JR, Slaton KB, Rhomberg ME, Ghahremani T, Thomas SL, Magann EF. Uterine Dehiscence and Subsequent Pregnancy Management: A Review of the Literature. Obstet Gynecol Surv 2021;76(1):48–54. doi: https://doi.org/10.1097/ogx.0000000000000856
Kennedy A, Debbink M, Griffith A, Kaiser J, Woodward P. Cesarean Scar Ectopic Pregnancy: A Do-Not-Miss Diagnosis. Radiographics 2024;44(7):e230199. doi: https://doi.org/10.1148/rg.230199
Huang J, Phillips C, Moshiri M. Scarred for life: a review of cesarean section scar pregnancy and potential pitfalls in diagnosis. Abdom Radiol (NY) 2023;48(8):2672–2683. doi: https://doi.org/10.1007/s00261-023-03953-7
Timor-Tritsch IE, Monteagudo A, Calì G, D’Antonio F, Kaelin Agten A. Cesarean Scar Pregnancy: Diagnosis and Pathogenesis. Obstet Gynecol Clin North Am 2019;46(4):797–811. doi: https://doi.org/10.1016/j.ogc.2019.07.009
Lin R, DiCenzo N, Rosen T. Cesarean scar ectopic pregnancy: nuances in diagnosis and treatment. Fertil Steril 2023;120(3 Pt 2):563–572. doi: https://doi.org/10.1016/j.fertnstert.2023.07.018
Liu L, Ross WT, Chu AL, Deimling TA. An updated guide to the diagnosis and management of cesarean scar pregnancies. Curr Opin Obstet Gynecol 2020;32(4):255–262. doi: https://doi.org/10.1097/gco.0000000000000644
Calì G, Timor-Tritsch IE, Palacios-Jaraquemada J, Monteaugudo A, Buca D, Forlani F, Familiari A, Scambia G, Acharya G, D’Antonio F. Outcome of Cesarean scar pregnancy managed expectantly: systematic review and meta-analysis. Ultrasound Obstet Gynecol 2018;51(2):169–175. doi: https://doi.org/10.1002/uog.17568
Abdelwahab M, Cackovic M. Placenta Accreta Spectrum and Postpartum Hemorrhage. Clin Obstet Gynecol 2023;66(2):399–407. doi: https://doi.org/10.1097/grf.0000000000000783
Horgan R, Abuhamad A. Placenta Accreta Spectrum: Prenatal Diagnosis and Management. Obstet Gynecol Clin North Am 2022;49(3):423–438. doi: https://doi.org/10.1016/j.ogc.2022.02.004
Shainker SA, Coleman B, Timor-Tritsch IE, Bhide A, Bromley B, Cahill AG, Gandhi M, Hecht JL, Johnson KM, Levine D, Mastrobattista J, Philips J, Platt LD, Shamshirsaz AA, Shipp TD, Silver RM, Simpson LL, Copel JA, Abuhamad A. Special Report of the Society for Maternal-Fetal Medicine Placenta Accreta Spectrum Ultrasound Marker Task Force: Consensus on definition of markers and approach to the ultrasound examination in pregnancies at risk for placenta accreta spectrum. Am J Obstet Gynecol 2021;224(1):B2-b14. doi: https://doi.org/10.1016/j.ajog.2020.09.001
Patel-Lippmann KK, Planz VB, Phillips CH, Ohlendorf JM, Zuckerwise LC, Moshiri M (2023) Placenta accreta spectrum disorders: update and pictorial review of the SAR-ESUR joint consensus statement for MRI. Radiographics. https://doi.org/10.1148/rg.220090
Gidwaney R, Badler RL, Yam BL, Hines JJ, Alexeeva V, Donovan V, Katz DS. Endometriosis of abdominal and pelvic wall scars: multimodality imaging findings, pathologic correlation, and radiologic mimics. Radiographics 2012;32(7):2031–2043. doi: https://doi.org/10.1148/rg.327125024
Zhang P, Sun Y, Zhang C, Yang Y, Zhang L, Wang N, Xu H. Cesarean scar endometriosis: presentation of 198 cases and literature review. BMC Womens Health 2019;19(1):14. doi: https://doi.org/10.1186/s12905-019-0711-8
Lyell DJ. Adhesions and perioperative complications of repeat cesarean delivery. Am J Obstet Gynecol 2011;205(6 Suppl):S11-18. doi: https://doi.org/10.1016/j.ajog.2011.09.029
Shafti V, Azarboo A, Ghaemi M, Gargari OK, Madineh E. Prediction of intraperitoneal adhesions in repeated cesarean sections: A Systematic review and Meta-analysis. Eur J Obstet Gynecol Reprod Biol 2023;287:97–108. doi: https://doi.org/10.1016/j.ejogrb.2023.05.039