Neurological disorders after hysterectomy: from pathogenesis to clinical manifestations

А. Г. Солопова, Д. В. Блинов, E. Begovich, L. N. Sandzhieva, S. V. Demyanov, G. V. Demyanov
In: Epilepsy and paroxysmal conditions · 2022 · vol. 14(1) , pp. 54–64 · doi:10.17749/2077-8333/epi.par.con.2022.115 · W4223959599
article OA: gold CC0 ⤵ 2 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This review details neurological disorders following hysterectomy, including chronic pain, nerve damage, and functional deficits, and explores their underlying mechanisms and emotional impact.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This paper is a narrative review examining neurological disorders that can occur after hysterectomy, focusing on chronic postoperative pain and other sequelae including traumatic neuroma, residual ovarian syndrome, mononeuropathies, sexual and sleep disorders, cognitive and motor changes, and lower urinary tract and bowel dysfunction. It synthesizes proposed mechanisms linking surgery to these outcomes, including the role of emotional disturbances, and highlights pathogenesis and clinical manifestations at a conceptual level. A major limitation is that, as a review of prior literature rather than an original cohort or experimental study, it does not provide new incidence estimates or standardized effect sizes, and it relies on heterogeneous evidence. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Hysterectomy currently occupies one of the leading places among obstetric and gynecological surgeries and is one of the highly effective and sometimes the only method of treating various diseases of the female genital organs. Quite often, however, hysterectomy results not only in the elimination of the cause of disease, but also in the development of complications that reduce the quality of life of patients. More and more attention is being paid to neurological complications, which is obviously due to improved diagnostic capabilities, as well as the results of recent research on the pathogenesis and treatment of neurological disorders. Only recently the scientists have begun to think about the true causes of one of the most important neurologic complications of hysterectomy, namely chronic postoperative pain. The review describes in detail the main neurological disorders that develop after hysterectomy: chronic postoperative pain, traumatic neuroma, residual ovarian syndrome as possible causes of chronic pain, mononeuropathies, sexual and sleep disorders, decreased cognitive and motor functions, lower urinary tract and bowel dysfunction. Considerable attention is given to the mechanisms of neurological complications and the relationship between the surgery and emotional disturbances in women.

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last seen: 2026-06-10T17:14:06.276822+00:00
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