Effect Of Danazol On Vocal Pitch - A Case-study

Mercaitis PA, P. A. Mercaitis, Peaper RE, R E Peaper, RE Peaper, Schwartz PA, PA Schwartz, P A Schwartz
Obstetrics and gynecology · 1985 · vol. 65(1) , pp. 131–5 · doi:10.7275/7784 · PMID:3966015 · W403795286
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Abstract

Acoustic analysis was used to measure fundamental frequency (vocal pitch in cycles per second) in a woman before, during, and after danazol therapy for endometriosis. A moderate lowering of fundamental frequency occurred within the three months of therapy and progressively lowered throughout the 5.5-month course. There was some action toward pretreatment levels, but 12 months after therapy, lowering of fundamental frequency persisted. The acceptability of this side effect and the need for further research are discussed.
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Condition tags

endometriosis

MeSH descriptors

Danazol Endometriosis Phonation Pregnadienes Vibration Vocal Cords Voice Adult Danazol Endometriosis Female Humans Phonation Pregnadienes Sound Spectrography Vocal Cords Voice

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