The rate of pregnancy following different treatment of endometriosis

А.А. Popov, О. В. Мачанските, Т. Н. Мананникова, G. G. Shaginyn, М. Р. Рамазанов
In: Journal of obstetrics and women's diseases · 2005 · vol. 54(5S) , pp. 46 · doi:10.17816/jowd87377 · W3211710681
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⚙ AI-generated summary by claude@2026-07, 2026-07-14 ⓘ

This study analyzed 401 patients undergoing surgery for endometriosis to determine pregnancy rates associated with various treatment approaches.

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⚙ AI-generated deep summary by claude@2026-07, 2026-07-14 · read from full text ⓘ

This paper reports on pregnancy outcomes after endometriosis surgery in 401 infertile patients (mean age 27.8) after excluding endocrine causes, comparing surgery alone versus surgery plus 6 months of Gn-RH agonist hormonal therapy. Pregnancy was achieved in 45.2% overall, and pregnancy frequency was reported as 18% higher in the combined-treatment group than in those receiving only surgical destruction of endometriosis lesions. The authors also state that most pregnancies occurred within the first six months after treatment, followed by a sharp decline. The paper presents these findings but does not specify key methodological details beyond group division, and it does not provide additional limitation statements in the provided text; This paper is centrally about endometriosis — it compares fertility/pregnancy rates following different endometriosis treatments.

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Abstract

Materials and methods. Endometriosis surgery was carried out in 401 patients.
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Abstract

Materials and methods. Endometriosis surgery was carried out in 401 patients. Full Text

Materials

and methods. Endometriosis surgery was carried out in 401 patients. Average age was 27,8 and all of them suffered from infertility for 2-5 years while endocrine factor was excluded. Patients were divided into two groups: a) surgical treatment only b) surgical treatment followed by hormonal therapy Gn-RH agonists for 6 months. Results. Pregnancy rate in patients with endometriosis associated infertility reached 45,2%. It was noted that pregnancy frequency in patients undergoing combined treatment was 18% higher that in patients which underwent only surgical destruction of the nidi. Majority of pregnancies occurred in the first six months following the treatment, after that pregnancy frequency sharply declined. Conclusion. Two stage treatment (1 - destruction of the endometriosis nodi, 2 - pharmocotheraphy) is pathognomonically substantiated. First stage envisages destruction of all or most of endometriosis nidi which cause number of condition leading to depressed generative function, while the second stage inactivates eutopic endometrium which is the constant source of endometriosis. About the authors A. A. Popov Moscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health and Social Development of the Russian Federation Author for correspondence. Email: [email protected] Russian Federation, Moscow О. V. Machanskite Moscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health and Social Development of the Russian Federation Email: [email protected] Russian Federation, Moscow Т. N. Manannikova Moscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health and Social Development of the Russian Federation Email: [email protected] Russian Federation, Moscow G. G. Shaginyn Moscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health and Social Development of the Russian Federation Email: [email protected] Russian Federation, Moscow М. R. Ramazanov Moscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health and Social Development of the Russian Federation Email: [email protected] Russian Federation, Moscow

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endometriosis

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