{"paper_id":"e49135a3-d36b-40b2-83f2-132751e2bcd9","body_text":"The rate of pregnancy following different treatment of endometriosis\n- Authors: Popov A.A.1, Machanskite О.V.1, Manannikova Т.N.1, Shaginyn G.G.1, Ramazanov М.R.1\n-\nAffiliations:\n- Moscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health and Social Development of the Russian Federation\n- Issue: Vol 54, No 5S (2005)\n- Pages: 46-46\n- Section: Reviews\n- Submitted: 15.11.2005\n- Accepted: 08.11.2021\n- Published: 15.11.2005\n- URL: https://journals.eco-vector.com/jowd/article/view/87377\n- DOI: https://doi.org/10.17816/JOWD87377\n- ID: 87377\nCite item\nAbstract\nMaterials and methods. Endometriosis surgery was carried out in 401 patients.\nFull Text\nMaterials and methods. Endometriosis surgery was carried out in 401 patients. Average age was 27,8 and all of them suffered from infertility for 2-5 years while endocrine factor was excluded. Patients were divided into two groups: a) surgical treatment only b) surgical treatment followed by hormonal therapy Gn-RH agonists for 6 months.\nResults. Pregnancy rate in patients with endometriosis associated infertility reached 45,2%. It was noted that pregnancy frequency in patients undergoing combined treatment was 18% higher that in patients which underwent only surgical destruction of the nidi. Majority of pregnancies occurred in the first six months following the treatment, after that pregnancy frequency sharply declined.\nConclusion. Two stage treatment (1 - destruction of the endometriosis nodi, 2 - pharmocotheraphy) is pathognomonically substantiated. First stage envisages destruction of all or most of endometriosis nidi which cause number of condition leading to depressed generative function, while the second stage inactivates eutopic endometrium which is the constant source of endometriosis.\nAbout the authors\nA. A. Popov\nMoscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health and Social Development of the Russian Federation\nAuthor for correspondence.\nEmail: info@eco-vector.com\nRussian Federation, Moscow\nО. V. Machanskite\nMoscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health and Social Development of the Russian Federation\nEmail: info@eco-vector.com\nRussian Federation, Moscow\nТ. N. Manannikova\nMoscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health and Social Development of the Russian Federation\nEmail: info@eco-vector.com\nRussian Federation, Moscow\nG. G. Shaginyn\nMoscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health and Social Development of the Russian Federation\nEmail: info@eco-vector.com\nRussian Federation, Moscow\nМ. R. Ramazanov\nMoscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health and Social Development of the Russian Federation\nEmail: info@eco-vector.com\nRussian Federation, Moscow","source_license":"CC0","license_restricted":false}