MODERN STRATEGY FOR THE MANAGEMENT OF CHRONIC PELVIC PAIN IN WOMEN WITH COMBINATIONS OF BENIGN UTERINE DISEASES

In: Scientific digest of association of obstetricians and gynecologists of Ukraine · 2019 · vol. 0(1(43)) , pp. 26–32 · doi:10.35278/2664-0767.1(43).2019.177826 · W3092283445
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AI-generated summary by claude@2026-06, 2026-06-06

This study developed and tested a treatment system for chronic pelvic pain in women with endometriosis and uterine fibroids, finding it reduced pain and improved psychoemotional states.

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AI-generated deep summary by claude@2026-06, 2026-06-09

The paper studied chronic pelvic pain in reproductive-age women with genital endometriosis combined with uterine leiomyoma and endometrial hyperplasia without atypia, analyzing treatment algorithms in 85 patients with severe pain (VAS 7–10; n=44) versus moderate pain (VAS 4–6; n=41). It found that long-term therapy with an intramuscular long-acting GnRH agonist (a-GnRH 3.6 mg) for 3–6 months combined with a levonorgestrel intrauterine system was the most effective scheme, and that the greatest reduction in personal anxiety at 12 months occurred with a-GnRH 3.6 mg for 3 months plus NSAIDs, dienogest 2 mg, or combined oral contraceptives containing dienogest for 12 months. Compared with traditional therapy, the proposed approach reported substantial pain intensity reduction in 83.53%, stabilization of psycho-emotional status in 93.30%, and a 3.9-fold decrease in chronic pelvic pain recurrence, though the paper provides no details on randomized design. This paper is centrally about endometriosis — it develops and evaluates a chronic pelvic pain management approach specifically for women with genital endometriosis alongside leiomyoma and endometrial hyperplasia.

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Abstract

Therapeutic approaches of chronic pelvic pain in women of reproductive age with genital endometriosis, in combination with uterine leomyoma, endometrial hyperplasia should be focused on the needs of patients for whom, in addition to preserving fertility, the elimination of pain and improvement of psychoemotional status is important.The objective the develop, clinically test a system of treatment and rehabilitation measures for chronic pelvic pain, taking into account pathogenetic prerequisites.Materials and methods The analysis of therapeutic algorithms of chronic pelvic pain in 85 patients with genital endometriosis in combination with uterine leiomyoma and endometrial hyperplasia without atypia with severe pelvic pain (VAS 7-10 points) (n = 44) - Group I and moderate pelvic pain ( n = 41) - group II c. The average age of women in the first and second clinical groups of the study was 37.71 ± 0.93 and 41.05 ± 1.08 (M ± m) years, respectively.Results. The most effective regimen in the longterm treatment agonists GnRH 3.6 mg 3–6 months. + LNG-IUS The highest rates of personal anxiety reduction on the J. Taylor scale (-56.26%) after 12 months were determined by a-GnRG with non-steroid anti-inflammatory drugs, Dienogest 2mg or hormonal contraceptives containing Dienogest 12 months.Conclusion The proposed approach to treating chronic pelvic pain significantly reduced the intensity of pain in 83.53% of women, stabilized the psychoemotional state in 93.30%, and reduced the recurrence of CPP by 3.9 times compared with women who received conventional therapy.

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Outcome instruments

VAS-pain

Condition tags

endometriosischronic_pelvic_pain

Citation neighborhood

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