Bladder endometriosis masquerading as recurrent urinary tract infection: successful fertility-preserving laparoscopic management

In: International Journal of Reproduction, Contraception, Obstetrics and Gynecology · 2026 · vol. 15(10) , pp. 4210–4213 · doi:10.18203/2320-1770.ijrcog20263476 · W7214594272
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Laparoscopic surgery and hormonal suppression successfully treated bladder endometriosis masquerading as recurrent urinary tract infection in a patient with concurrent adenomyosis, preserving fertility.

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This case report describes a 38-year-old woman presenting with recurrent dysuria and severe dysmenorrhea, initially misdiagnosed as urinary tract infection. Pelvic MRI and cystoscopy identified deep infiltrating endometriosis involving the posterior bladder wall, bilateral ovarian endometriomas, adenomyosis, and rectosigmoid serosal involvement. The patient underwent successful fertility-preserving laparoscopic surgery including partial cystectomy, adenomyomectomy, and excision of deep infiltrating lesions, resulting in resolution of symptoms. This paper is centrally about endometriosis — specifically bladder involvement and concurrent adenomyosis managed via laparoscopic excision.

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Abstract

Urinary tract endometriosis is an uncommon manifestation of deep infiltrating endometriosis, accounting for approximately 1% of all endometriosis cases, with the bladder being the most frequently involved urinary organ. Because its symptoms often mimic recurrent urinary tract infection or bladder pain syndrome, diagnosis is frequently delayed. A 38-year-old woman presented with recurrent dysuria, severe dysmenorrhea and urinary frequency for one year despite repeated medical treatment. Pelvic MRI demonstrated deep infiltrating endometriosis involving the posterior bladder wall with associated bilateral ovarian endometriomas, adenomyosis and rectosigmoid serosal involvement. Cystoscopy revealed a bluish submucosal lesion over the posterior bladder wall with sparing of the trigone. The patient underwent laparoscopic bilateral ovarian cystectomy, excision of deep infiltrating endometriosis, bilateral ureterolysis, adenomyomectomy and laparoscopic partial cystectomy with two-layer bladder repair. Histopathology confirmed bladder endometriosis. The postoperative course was uneventful, and urinary symptoms resolved following catheter removal and hormonal suppression with dienogest. Bladder endometriosis should be considered in women with persistent lower urinary tract symptoms refractory to conventional treatment, particularly when associated with pelvic pain or dysmenorrhea. Early MRI evaluation and multidisciplinary laparoscopic surgery allow complete excision while preserving fertility.
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Bladder endometriosis masquerading as recurrent urinary tract infection: successful fertility-preserving laparoscopic management DOI: https://doi.org/10.18203/2320-1770.ijrcog20263476Keywords: Bladder endometriosis, Deep infiltrating endometriosis, Partial cystectomy, Laparoscopy, Chronic urinary tract infection, Fertility preservationAbstract Urinary tract endometriosis is an uncommon manifestation of deep infiltrating endometriosis, accounting for approximately 1% of all endometriosis cases, with the bladder being the most frequently involved urinary organ. Because its symptoms often mimic recurrent urinary tract infection or bladder pain syndrome, diagnosis is frequently delayed. A 38-year-old woman presented with recurrent dysuria, severe dysmenorrhea and urinary frequency for one year despite repeated medical treatment. Pelvic MRI demonstrated deep infiltrating endometriosis involving the posterior bladder wall with associated bilateral ovarian endometriomas, adenomyosis and rectosigmoid serosal involvement. Cystoscopy revealed a bluish submucosal lesion over the posterior bladder wall with sparing of the trigone. The patient underwent laparoscopic bilateral ovarian cystectomy, excision of deep infiltrating endometriosis, bilateral ureterolysis, adenomyomectomy and laparoscopic partial cystectomy with two-layer bladder repair. Histopathology confirmed bladder endometriosis. The postoperative course was uneventful, and urinary symptoms resolved following catheter removal and hormonal suppression with dienogest. Bladder endometriosis should be considered in women with persistent lower urinary tract symptoms refractory to conventional treatment, particularly when associated with pelvic pain or dysmenorrhea. Early MRI evaluation and multidisciplinary laparoscopic surgery allow complete excision while preserving fertility. Metrics References Kho Lily CL, Goh C, Lim YK. Isolated Bladder Endometriosis in a Patient with Previous Cesarean Sections. J Med Cases. 2020;11(11):370-3. DOI: https://doi.org/10.14740/jmc3543 Salmeri N, Buffo C, Ragusi A, Somigliana E, Viganò P, Vercellini P. Postcesarean Versus Primary Bladder Endometriosis and Coexistent Pelvic Endometriosis: A Systematic Review. J Minim Invasive Gynecol. 2026;33(2):178-86. DOI: https://doi.org/10.1016/j.jmig.2025.08.012 Tawashi K, Alhamid AAH, Alabdullah H, Belal M, Almassri MN, Lutfi MY. Bladder endometriosis in a patient with undirected manifestations: a case report. J Med Case Rep. 2025;19(1):286. DOI: https://doi.org/10.1186/s13256-025-05337-5 Vercellini P, Meschia M, De Giorgi O, Panazza S, Cortesi I, Crosignani PG. Bladder detrusor endometriosis: clinical and pathogenetic implications. J Urol. 1996;155(1):84-6. DOI: https://doi.org/10.1016/S0022-5347(01)66550-9 Beaty SD, Silva AC, De Petris G. Bladder endometriosis: ultrasound and MRI findings. Radiol Case Rep. 2015;1(3):92-5. DOI: https://doi.org/10.2484/rcr.v1i3.16 Rolla E. Endometriosis: advances and controversies in classification, pathogenesis, diagnosis, and treatment. F1000Res. 2019;8:F1000. DOI: https://doi.org/10.12688/f1000research.14817.1 Leone Roberti Maggiore U, Ferrero S, Candiani M, Somigliana E, Viganò P, Vercellini P. Bladder Endometriosis: A Systematic Review of Pathogenesis, Diagnosis, Treatment, Impact on Fertility, and Risk of Malignant Transformation. Eur Urol. 2017;71(5):790-807. DOI: https://doi.org/10.1016/j.eururo.2016.12.015 Piriyev E, Schiermeier S, Römer T. Bladder Endometriosis: Diagnostic, Therapy, and Outcome of a Single-Center Experience. Diagnostics (Basel). 2025;15(4):466. DOI: https://doi.org/10.3390/diagnostics15040466 Downloads Published How to Cite Issue Section License Copyright (c) 2026 Raksha Gaikar, Niteen Ghorpade, Krunal Yerne This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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