Comparison of the symptoms and localisation of endometriosis involvement according to fertility status of endometriosis patients

Fatemeh Aliani, Mahnaz Ashrafi, Arezoo Arabipoor, Ensieh Shahrokh-Tehraninejad, Shahideh Jahanian Sadatmahalleh, Mohammad Reza Akhond
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology · 2018 · vol. 38(4) , pp. 536–542 · doi:10.1080/01443615.2017.1374933 · PMID:29390906 · W2792294207
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This study compared endometriosis symptoms and lesion locations in fertile and infertile women, finding infertility more prevalent with peritoneal endometriosis and pain symptoms more prevalent with ovarian and peritoneal implants.

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Abstract

This cross-sectional study aimed to assess the prevalence of endometriosis in women who were referred for Diagnostic Laparoscopy Unit due to infertility or pelvic pain between January 2012 and January 2013 and compare the symptoms and laparoscopic signs among the three groups according to the fertility status. Four hundred and thirteen women were evaluated; of these, 383 patients for infertility and 30 patients for pelvic pain and/or cyst. Endometriosis symptoms were compared between fertile and infertile women with primary and secondary infertility. There was no statistically significant difference in the overall prevalence of endometriosis between the three study groups (52.9%, 45% and 40.7%, respectively, in primary, secondary infertile and fertile women). The endometriosis stage was categorised as early- (I and II) or late- (III and IV) stages and the extent of endometriosis was divided into peritoneal, ovarian and ovarian coexisting with peritoneal. There is no relationship between the frequency of dysmenorrhoea or non-cyclic pelvic pain and the disease stage; although these pain symptoms are significantly more prevalent in cases with both ovarian and peritoneal endometriotic implants. Infertility was more prevalent among the patients with peritoneal endometriosis in comparison to the ones with ovarian endometriosis. Further studies with a larger sample size are required to confirm these findings. Impact statement What is already known on this subject? Few studies have been done in this area and only one study compared the localisation of endometriosis lesions between fertile and infertile endometriosis cases; however, more study is needed to confirm their results. What the results of this study add? A possible relationship between localisation of endometriosis involvement and infertility was found in the present study in agreement to result of a previous study performance in this area. Although the present study includes a greater number of cases than that of the previous reported study, further studies with a larger sample size are required for the confirmation or refusal of this finding. What are the implications of these findings for clinical practice and/or further research? The results of this study could have clinical application in the consultation and decision-making in infertile women with an endometriosis diagnosis.

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Condition tags

endometriosischronic_pelvic_paindysmenorrheainfertility

MeSH descriptors

Endometriosis Infertility, Female Adult Cross-Sectional Studies Endometriosis Endometriosis Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female Infertility, Female Iran Iran Laparoscopy Ovary Ovary Pelvic Pain Pelvic Pain

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