Recurrent acute kidney injury in a young female: A rare presentation of ureteral endometriosis

Case report OA: diamond CC0 ⤵ 1 in-corpus citation
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This prospective observational study evaluated the feasibility and clinical outcomes of peritoneal dialysis in 51 patients with end-stage renal disease, chronic liver disease, and ascites.

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This prospective observational study evaluated the feasibility and clinical outcomes of peritoneal dialysis in 51 patients with end-stage renal disease complicated by chronic liver disease and ascites. The researchers compared these patients to a control group of 55 individuals with end-stage renal disease but without liver disease, noting successful catheter insertion and comparable rates of peritonitis between the two cohorts. While the procedure appeared feasible with manageable complications such as transient albumin decline and early dialysate leakage, the authors explicitly cautioned that the descriptive findings do not establish safety or effectiveness. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Objectives

Patients with chronic liver disease (CLD) complicated by ascites may develop end-stage renal disease (ESRD), making selection of renal replacement therapy challenging. This study described the feasibility and clinical outcomes of peritoneal dialysis (PD) in selected patients with ESRD, CLD, and ascites. Patients and Methods: This prospective observational study included 51 selected patients with ESRD, CLD, and ascites and 55 patients with ESRD without CLD who underwent PD at a tertiary university hospital in Saudi Arabia. All underwent percutaneous insertion of a three-cuff PD catheter and received automated peritoneal dialysis (APD). Clinical outcomes recorded during observed follow-up are presented descriptively.

Results

Percutaneous catheter insertion was successful in all patients without bowel perforation, catheter migration, or major hemorrhage. Thirteen peritonitis episodes were recorded in the CLD group and 12 in the non-CLD group. The overall peritonitis rate was 0.10 episodes per patient-year; group-specific rates were 0.11 and 0.09 episodes per patient-year, respectively. None required catheter removal. A transient serum albumin decline of at least 0.5 g/dL was recorded in 5 and 4 patients, respectively. Early dialysate leakage occurred in 7/51 and 3/55 patients and was managed by temporary reduction of fill volume. During observed follow-up, 12/51 patients with CLD and 9/55 patients without CLD died.

Conclusions

Peritoneal dialysis was feasible in this selected cohort of patients with ESRD, chronic liver disease, and ascites. The observed adequacy values, complication counts, and crude mortality are reported descriptively. The findings should not be interpreted as establishing safety, effectiveness, equivalence, or superiority.

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Condition tags

endometriosis

MeSH descriptors

Acute Kidney Injury Endometriosis Ureteral Diseases Ureteral Obstruction Acute Kidney Injury Acute Kidney Injury Acute Kidney Injury Acute Kidney Injury Adult Adult Endometriosis Endometriosis Endometriosis Endometriosis Female Female Humans Humans Recurrence Recurrence

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References (13)

Cited by (1)

Source provenance

europepmc
last seen: 2026-10-08T06:18:23.926119+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:17:32.889250+00:00
License: CC0 · commercial use OK