The Predictive Potential of Peripheral Blood Basophils in Endometriosis.

Jian‐Long Guan, Karin Hellner, Nilüfer Rahmioğlu, Carol Hubbard, M. Maureen Dale, Kevin Paddon, Krina T. Zondervan, Christian M. Becker
2017 · vol. 24 · W2766171788
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This prospective study investigated whether peripheral blood leukocyte subpopulations, specifically basophils, could serve as non-invasive diagnostic markers for endometriosis by analyzing data from the ENDOX study.

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This conference abstract investigates whether peripheral blood leukocyte subpopulations can serve as diagnostic markers for endometriosis, a condition currently requiring surgical confirmation. The researchers utilized data from the prospective ENDOX study to evaluate the predictive potential of circulating immune cells, specifically focusing on basophils, given the known systemic inflammatory nature of the disease. While the text highlights the urgent need for less invasive diagnostic tools, it does not report specific statistical results or conclude on the efficacy of basophils in this brief summary. This paper is centrally about endometriosis — specifically exploring novel non-invasive biomarkers for its diagnosis.

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Abstract

Endometriosis affects 5-10% of premenopausal women causing pelvic pain and impaired fertility. Diagnosis can only be established surgically, thus, less invasive means of diagnosis are urgently needed. Endometriosis has been suggested to induce local and systemic inflammation. Circulating leukocytes are used as markers of systemic inflammatory response in many conditions. However, their role in endometriosis is unclear. This study investigates the potential of leukocyte subpopulations in diagnosing endometriosis, using data from prospective ENDOX study.
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Conference item The predictive potential of peripheral blood basophils in endometriosis - Abstract: - Endometriosis affects 5-10% of premenopausal women causing pelvic pain and impaired fertility. Diagnosis can only be established surgically, thus, less invasive means of diagnosis are urgently needed. Endometriosis has been suggested to induce local and systemic inflammation. Circulating leukocytes are used as markers of systemic inflammatory response in many conditions. However, their role in endometriosis is unclear. This study investigates the potential of leukocyte subpopulations in diagnosing endometriosis, using data from prospective ENDOX study. - Publication status: - Published - Peer review status: - Peer reviewed Actions Access Document - Files: - - (Preview, Accepted manuscript, pdf, 178.6KB, Terms of use) - - Publisher copy: - 10.1177/1933719117699773 Authors - Publisher: - SAGE Publications - Host title: - 64th Annual Meeting of the Society for Reproductive Investigation (SRI 2017) - Journal: - 64th Annual Meeting of the Society for Reproductive Investigation (SRI 2017) More from this journal - Publication date: - 2017-03-01 - Acceptance date: - 2017-01-06 - DOI: - Pubs id: - pubs:718621 - UUID: - uuid:881974a5-4dc4-4164-81d3-36bf466786e9 - Local pid: - pubs:718621 - Source identifiers: - 718621 - Deposit date: - 2018-06-19 - ARK identifier: Terms of use - Copyright holder: - Society for Reproductive Investigation - Copyright date: - 2017 - Notes: - Copyright © 2018 by Society for Reproductive Investigation. This is the accepted manuscript version of the article. The final version is available online from SAGE Publications at: https://doi.org/10.1177/1933719117699773 If you are the owner of this record, you can report an update to it here: Report update to this record

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