Effect of levonorgestrel-releasing intrauterine system in the treatment of adenomyosis

何淑明, 韦明秀, 韩燕华, 何立红
In: Chin J Obstet Gynecol · 2005 · vol. 40(08) , pp. 536–538 · doi:10.3760/j.issn:0529-567x.2005.08.009 · W3032440736
article OA: closed CC0 ⤵ 11 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-10 ⓘ

Levonorgestrel-releasing intrauterine system treatment of adenomyosis significantly reduced menstrual bleeding, uterine volume, and dysmenorrhea, with anemic patients showing improved hemoglobin levels.

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⚙ AI-generated deep summary by claude@2026-07, 2026-07-04 · read from full text ⓘ

The paper evaluated the clinical efficacy of a levonorgestrel-releasing intrauterine system (LNG-IUS; Mirena) for treating adenomyosis in 42 patients diagnosed by clinical symptoms plus color ultrasound or MRI and confirmed using laparoscopy or open surgery. After LNG-IUS placement, outcomes included menstrual blood loss, dysmenorrhea severity, and uterine volume measured over a 3-month follow-up. At 3 months, menstrual blood loss decreased to about 27±11% of baseline, uterine volume fell from 143±33 cm3 to 115±22 cm3, and dysmenorrhea was significantly improved or resolved in all patients, with hemoglobin recovering in 20 anemic patients. The paper states overall that the recent treatment effect was significant, but it is limited by its short observation period and lacks a control/comparator group. This paper is centrally about adenomyosis — it specifically examines LNG-IUS clinical outcomes in patients with uterine adenomyosis.

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Abstract

目的 探讨左炔诺孕酮宫内缓释系统(LNG-IUS;商品名:曼月乐)治疗子宫腺肌病的临床疗效.方法对42例根据临床症状、彩色超声或MRI检查、腹腔镜或开腹手术诊断为子宫腺肌病的患者,宫内放置LNG-IUS,观察月经量、痛经程度及子宫体积变化.结果放置LNG-IUS后3个月,月经量显著减少,治疗3个月时的月经量降低为治疗前的(27±11)%,治疗前后比较,差异有统计学意义(P＜0.01);治疗前子宫体积为(143±33) cm3,治疗3个月时子宫体积为(115±22) cm3,治疗前后比较,差异也有统计学意义(P＜0.05);42例患者痛经症状显著缓解或完全消失;20例贫血患者血红蛋白水平从治疗前的(86±14) g/L恢复至治疗后的(124±8) g/L.结论 LNG-IUS治疗子宫腺肌病近期疗效显著。
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左炔诺孕酮宫内缓释系统治疗子宫腺肌病的临床观察 Effect of levonorgestrel-releasing intrauterine system in the treatment of adenomyosis 摘要目的探讨左炔诺孕酮宫内缓释系统(LNG-IUS;商品名:曼月乐)治疗子宫腺肌病的临床疗效.方法对42例根据临床症状、彩色超声或MRI检查、腹腔镜或开腹手术诊断为子宫腺肌病的患者,宫内放置LNG-IUS,观察月经量、痛经程度及子宫体积变化.结果放置LNG-IUS后3个月,月经量显著减少,治疗3个月时的月经量降低为治疗前的(27±11)%,治疗前后比较,差异有统计学意义(P＜0.01);治疗前子宫体积为(143±33) cm3,治疗3个月时子宫体积为(115±22) cm3,治疗前后比较,差异也有统计学意义(P＜0.05);42例患者痛经症状显著缓解或完全消失;20例贫血患者血红蛋白水平从治疗前的(86±14) g/L恢复至治疗后的(124±8) g/L.结论 LNG-IUS治疗子宫腺肌病近期疗效显著. 更多相关知识 - 浏览842 - 被引140 - 下载940 相似文献 - 中文期刊 - 外文期刊 - 学位论文 - 会议论文

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adenomyosis

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