Impact of adenomyosis on pregnancy outcomes: a retrospective consecutive cohort study

L-S Chen, Chen LS, L Chen, X Chen, Xuyu Chen, Chen X, J-R Song, Song JR, Zhuang YL, Y-L Zhuang, Xin Xie, X Xie, Xie X, Shing‐Hwa Liu, Liu SH, S-H Liu, Zheng Xq, X-Q Zheng, Hang Yi, H Yi, Yi H, Zhang YL, YL Zhang, Y-L Zhang
European review for medical and pharmacological sciences · 2024 · vol. 28(2) , pp. 577–583 · doi:10.26355/eurrev_202401_35055 · PMID:38305602 · W4394750555
article OA: closed CC0 ⤵ 1 in-corpus citation
Full text JSON View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This study found that adenomyosis correlated with increased risks of gestational hypertension, gestational diabetes, placenta previa, postpartum hemorrhage, low fetal weight, and low APGAR scores, but a decreased risk of premature rupture of membranes.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

This retrospective consecutive cohort study analyzed 1,208 pregnancies, comparing 334 women diagnosed with adenomyosis to 874 women with uncomplicated pregnancies, and assessed maternal and neonatal outcomes as well as pregnancy complications. The adenomyosis group had higher incidences of gestational hypertension, gestational diabetes, and placenta previa (p<0.05). Adenomyosis was associated with a higher risk of postpartum hemorrhage (1,000–1,500 ml) and a lower risk of premature rupture of membranes, and it also correlated with low fetal weight and lower APGAR scores at 1 minute. The paper’s main limitation, as stated by its retrospective design, is that data were collected retrospectively and cannot establish causality, and it does not describe how key confounders were controlled. This paper is centrally about adenomyosis — it evaluates how adenomyosis impacts pregnancy outcomes and specific complications.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

OBJECTIVE: This retrospective study explored the potential connection between adenomyosis and pregnancy outcomes. PATIENTS AND METHODS: A study included data from a total of 1,208 pregnancies. The adenomyosis group included 334 pregnant women with adenomyosis, and women in the control group (n=874) had uncomplicated pregnancies. Data on pregnancy complications and maternal and neonatal outcomes were compared. RESULTS: The incidence of gestational hypertension, gestational diabetes, and placenta previa was higher in the adenomyosis group compared to the control group (p<0.05). Adenomyosis was linked to a higher risk of postpartum hemorrhage (1,000-1,500 ml) but a lower risk of premature rupture of membranes (PROM) (p<0.05). Diagnosis of adenomyosis correlated with increased incidence of low fetal weight (20.3% vs. 21.3%, p<0.05) and a low APGAR score at 1 min (p<0.05). CONCLUSIONS: Adenomyosis correlated with a higher incidence of gestational hypertension, placenta previa, and gestational diabetes. At the same time, adenomyosis correlated with a significantly lower incidence of PROM compared to uncomplicated pregnancy. There was a significant increase in the incidence of postpartum hemorrhage and a higher risk of low fetal weight and lower APGAR score at 1 min in pregnancies with adenomyosis.
Full text 2,157 characters · extracted from oa-doi-fallback · 3 sections · click to expand

Objective

This retrospective study explored the potential connection between adenomyosis and pregnancy outcomes. PATIENTS AND METHODS: A study included data from a total of 1,208 pregnancies. The adenomyosis group included 334 pregnant women with adenomyosis, and women in the control group (n=874) had uncomplicated pregnancies. Data on pregnancy complications and maternal and neonatal outcomes were compared.

Results

The incidence of gestational hypertension, gestational diabetes, and placenta previa was higher in the adenomyosis group compared to the control group (p<0.05). Adenomyosis was linked to a higher risk of postpartum hemorrhage (1,000-1,500 ml) but a lower risk of premature rupture of membranes (PROM) (p<0.05). Diagnosis of adenomyosis correlated with increased incidence of low fetal weight (20.3% vs. 21.3%, p<0.05) and a low APGAR score at 1 min (p<0.05).

Conclusions

Adenomyosis correlated with a higher incidence of gestational hypertension, placenta previa, and gestational diabetes. At the same time, adenomyosis correlated with a significantly lower incidence of PROM compared to uncomplicated pregnancy. There was a significant increase in the incidence of postpartum hemorrhage and a higher risk of low fetal weight and lower APGAR score at 1 min in pregnancies with adenomyosis. Free PDF DownloadThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License To cite this article L.-S. Chen, X. Chen, J.-R. Song, Y.-L. Zhuang, X. Xie, S.-H. Liu, X.-Q. Zheng, H. Yi, Y.-L. Zhang Impact of adenomyosis on pregnancy outcomes: a retrospective consecutive cohort study Eur Rev Med Pharmacol Sci Year: 2024 Vol. 28 - N. 2 Pages: 577-583 DOI: 10.26355/eurrev_202401_35055 Publication History Published online: 31 Jan 2024

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cited by (1)

Cited by (1)

Source provenance

europepmc
last seen: 2026-07-29T06:27:48.050232+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-07-29T06:25:59.535416+00:00
License: CC0 · commercial use OK