Successful use of botulinum toxin type a in the treatment of refractory postoperative dyspareunia

Case report OA: closed CC0 ⤵ 2 in-corpus citations
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Botulinum toxin type A injections into the levator ani muscles successfully treated refractory postoperative vaginismus and dyspareunia in a patient who did not respond to conservative therapies.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-22 · read from full text ⓘ

This case report describes a woman with stage 2 prolapse and defecatory dysfunction who underwent laparoscopic pelvic floor reconstruction and excision of endometriosis. Postoperatively, she developed refractory dyspareunia and de novo vaginismus that failed to respond to trigger point injections, physical therapy, and other medical or surgical interventions. The patient subsequently received botulinum toxin type A injections into her levator ani muscles, which restored sexual function for twelve months without pain recurrence. This paper is centrally about endometriosis — specifically the postoperative management of complications following the excision of endometriosis lesions.

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Abstract

BACKGROUND: Refractory dyspareunia presents a challenging therapeutic dilemma. CASE: A woman with defecatory dysfunction and dyspareunia presented with stage 2 prolapse. She underwent laparoscopic and vaginal pelvic floor reconstruction with excision of endometriosis. The patient experienced increased dyspareunia and de novo vaginismus postoperatively that were refractory to trigger point injections, physical therapy, and medical and surgical management. She underwent botulinum toxin type A injections into her levator ani muscles, which allowed her to have sexual intercourse again after 2 years of apareunia with no recurrence of pain for 12 months. CONCLUSION: Injecting botulinum toxin into the levator ani muscles shows promise for postoperative patients who develop vaginismus and do not respond to conservative therapy.
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Background

Refractory dyspareunia presents a challenging therapeutic dilemma. CASE: A woman with defecatory dysfunction and dyspareunia presented with stage 2 prolapse. She underwent laparoscopic and vaginal pelvic floor reconstruction with excision of endometriosis. The patient experienced increased dyspareunia and de novo vaginismus postoperatively that were refractory to trigger point injections, physical therapy, and medical and surgical management. She underwent botulinum toxin type A injections into her levator ani muscles, which allowed her to have sexual intercourse again after 2 years of apareunia with no recurrence of pain for 12 months.

Conclusion

Injecting botulinum toxin into the levator ani muscles shows promise for postoperative patients who develop vaginismus and do not respond to conservative therapy.

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Condition tags

dyspareuniaendometriosis

MeSH descriptors

Botulinum Toxins, Type A Dyspareunia Dyspareunia Neuromuscular Agents Postoperative Complications Postoperative Complications Vaginismus Botulinum Toxins, Type A Botulinum Toxins, Type A Dyspareunia Dyspareunia Endometriosis Endometriosis Endometriosis Female Female Humans Humans Middle Aged Middle Aged

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Source provenance

europepmc
last seen: 2026-10-12T06:17:10.165071+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-10-08T21:06:42.330992+00:00
License: CC0 · commercial use OK