Successful Use of Botulinum Toxin Type A in the Treatment of Refractory Postoperative Dyspareunia

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Abstract

In Brief BACKGROUND: Refractory dyspareunia presents a challenging therapeutic dilemma. CASE: A woman with defecatory dysfunction and dyspareunia presented with stage 2 prolapse. She underwent laparoscopic and vaginal pelvic floor reconstruction with excision of endometriosis. The patient experienced increased dyspareunia and de novo vaginismus postoperatively that were refractory to trigger point injections, physical therapy, and medical and surgical management. She underwent botulinum toxin type A injections into her levator ani muscles, which allowed her to have sexual intercourse again after 2 years of apareunia with no recurrence of pain for 12 months. CONCLUSION: Injecting botulinum toxin into the levator ani muscles shows promise for postoperative patients who develop vaginismus and do not respond to conservative therapy. Injecting botulinum toxin into the levator ani muscles shows promise for postoperative patients who develop vaginismus and do not respond to conservative therapy.

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Condition tags

dyspareuniaendometriosis

MeSH descriptors

Botulinum Toxins, Type A Dyspareunia Dyspareunia Neuromuscular Agents Postoperative Complications Vaginismus Botulinum Toxins, Type A Dyspareunia Endometriosis Endometriosis Female Humans Middle Aged Neuromuscular Agents Pelvic Floor Pelvic Floor Rectocele Rectocele Uterine Prolapse Uterine Prolapse

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europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
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pubmed
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License: CC0 · commercial use OK