Identification of ovarian endometriotic cysts in cystic lesions of the ovary by amide proton transfer-weighted imaging and R2∗ mapping

Y. Li, Yuming Li, Li Y, Xinguo Lu, Lu X, X Lu, L Chen, Chen L, Liming Chen, Q. Zhang, Zhang Q, Qingyu Zhang, N. Wang, Wang N, Wang J, J. Wang, L Lin, Liangjie Lin, Lin L, G Hu, Hu G, Zhang Y, Y Zhang, A Liu, An-Ning Liu, Liu A
Clinical Radiology · 2022 · vol. 78(2) , pp. e106–e112 · doi:10.1016/j.crad.2022.09.117 · PMID:36334944 · W4308112381
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Amide proton transfer-weighted imaging and R2∗ mapping of ovarian endometriotic cysts revealed lower APTw and higher R2∗ values compared to other ovarian cystic lesions, achieving high diagnostic efficacy for differentiation.

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Abstract

AIM: To investigate the value of amide proton transfer weighted (APTw) imaging and R2∗ mapping of cystic fluid in differentiating ovarian endometriotic cysts (OE) from other ovarian cystic (OOC) lesions. MATERIALS AND METHODS: A total of 42 patients who underwent 3 T pelvic magnetic resonance imaging (MRI) were enrolled. Nineteen lesions were OE and 27 lesions were OOC. The APTw imaging and R2∗ values of the cystic fluid were measured and compared between the two groups using the independent sample t-test or Mann-Whitney U-test. Receiver operating characteristic (ROC) curves were used to evaluate the diagnostic efficacy of different parameters. The area under ROC curves (AUCs) was compared using the Delong test. Spearman's correlation analysis was used to assess the correlation between APTw imaging and R2∗ values. RESULTS: APTw imaging values of OE were lower, while R2∗ values were higher in OE than those in OOC (p=0.001 and < 0.001). The AUCs of APTw imaging and R2∗ values to identify OE from OOC were 0.910 and 0.975. The AUC increased to 0.990 when combining APTw imaging and R2∗ values, yet without a significant difference to the APTw imaging or R2∗ value alone (p=0.229 and 0.082, respectively). APTw imaging values were negatively correlated with R2∗ values (r=-0.522, p<0.001). CONCLUSION: Both APTw imaging and R2∗ values of OE are significantly different from other ovarian cystic lesions. APTw imaging combined with R2∗ values show excellent diagnostic efficacy to differentiate between OE and OOC.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

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SciLite annotations

chemicals 2
amide amide

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