PCR Genetic Expression of Interleukin 37 in the Eutopic and Ectopic Endometrium of Women with Endometriosis
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Interleukin 37 mRNA expression was significantly higher in both ectopic and eutopic endometrium of endometriosis patients compared to controls.
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Abstract
Background: In endometriosis, there is a chronic immune and inflammatory reaction. Objective: To study the PCR genetic expression of interleukin 37 in the eutopic and ectopic endometrium of women with endometriosis in comparison with controls. Patient and Methods: Forty-six patients were included in the study. Twenty-three women diagnosed as endometriosis and twenty-three women diagnosed as free of endometriosis were subjected to laparoscopy for any other gynecological cause. Interleukin 37 gene expression was studied in ectopic and eutopic endometrium using polymerase chain reaction. Results: Ectopic endometrium expressed high levels of mRNA compared to eutopic endometrium in endometriosis patients. Eutopic endometrium of endometriosis patients expressed high levels of mRNA compared to eutopic endometrium of controls. Conclusion: The finding of high mRNA produced in endometrial tissue suggests that interleukin 37 may be important in the chronic inflammation occurring during endometriosis.
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References (18)
- Cytokine profiles in serum and peritoneal fluid from infertile women with and without endometriosis via openalex
- Endometriosis and Infertility via openalex
- Genetics and Genomics of Endometriosis via openalex
- How Artificial Intelligence Can Improve Our Understanding of the Genes Associated with Endometriosis: Natural Language Processing of the PubMed Database via openalex
- Increased Expression of Interleukin 37 in the Eutopic and Ectopic Endometrium of Patients With Ovarian Endometriosis via openalex
- Serum and peritoneal fluid levels of interleukin-6 and interleukin-37 as biomarkers for endometriosis via openalex
- Serum cytokine and growth factor levels in patients with endometriosis via openalex
- W2596152408 via openalex
- W2786886706 via openalex
- W6670129878 via openalex
- W1966098682 via openalex
- W6735052411 via openalex
- W2079190330 via openalex
- W2093194698 via openalex
- W2144421609 via openalex
- W2149624733 via openalex
- W2333441487 via openalex
- W2595044230 via openalex
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