Qualität der klinischen Diagnose der Endometriose

The study evaluated the sensitivity and specificity of preoperative clinical diagnosis of endometriosis using retrospective data from 543 women aged 16–55 who underwent surgery at the University Women’s Clinic in Lübeck (2005–2006). Women were included if their referral and/or operative diagnosis was endometriosis, and controls were women with benign lower-belly gynecologic conditions in whom endometriosis was excluded surgically; 156 had endometriosis (101 first diagnosis, 55 recurrence). Only 42.6% of first-diagnosis cases had endometriosis suspected before surgery in the clinic (29.7% by outside specialists), whereas in recurrence cases suspicion rates were much higher (89.1% clinic, 74.5% specialists); clinical preoperative sensitivity was 70.9% in the clinic and 63.7% for specialists, with high specificity (95.6% and 96.9%, respectively). The paper emphasizes low sensitivity for initial diagnosis and calls for improved noninvasive diagnostics. This paper is centrally about endometriosis—evaluating the diagnostic quality (sensitivity/specificity) of preoperative clinical suspicion in routine practice.

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