Pelvic denervation for chronic pain associated with endometriosis: fact or fancy?

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This review analyzes presacral neurectomy and uterosacral ligament amputation for endometriosis-associated chronic pelvic pain, finding no proven efficacy for these denervation procedures regardless of surgical method.

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Abstract

The efficacy of presacral neurectomy and amputation of the uterosacral ligaments in the treatment of chronic pelvic pain has been debated for decades. These procedures used to be done mainly in women with normal pelves, but more recently they have been performed during conservative surgery for treatment of endometriosis. In the 1980s the rapid spread of laparoscopic surgery has led to an increasing number of endoscopic denervations in patients with chronic pelvic pain associated with endometriosis. However, an analysis of literature data has failed to prove that presacral neurectomy and amputation of the uterosacral ligaments are effective and did not demonstrate better results with the use of lasers rather than electrocoagulation. Moreover, no valid comparison has yet been made between laparotomy and laparoscopic methods.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Denervation Endometriosis Pain Management Pelvis Chronic Disease Endometriosis Female Humans Laparoscopy Laparotomy Ligaments Ligaments Pelvis

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europepmc
last seen: 2026-10-05T06:18:27.067365+00:00
pubmed
last seen: 2026-05-13T22:11:54.876058+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine