Obstetrics and gynecology in Ehlers‐Danlos syndrome: A brief review and update

Natalie Blagowidow
American journal of medical genetics. Part C, Seminars in medical genetics · 2021 · vol. 187(4) , pp. 593–598 · doi:10.1002/ajmg.c.31945 · PMID:34773390 · W3214066772
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⚙ AI-generated summary by claude@2026-06, 2026-06-11 ⓘ

Ehlers-Danlos syndromes affect connective tissue, increasing obstetric and gynecologic complication risks, though some conditions may be less frequent than previously believed and anticipatory planning can reduce morbidity.

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Abstract

The Ehlers-Danlos syndromes (EDSs) are a group of hereditary disorders affecting collagen and connective tissue. Gynecologic and obstetric complications occur with increased frequency and severity due to these abnormalities. Recent studies suggest that some complications, including endometriosis and premature rupture of the membranes may occur less often than previously thought. In addition, having a known diagnosis allows anticipatory planning, resulting in lower morbidity from hemorrhage and tissue injury. With continued progress in understanding the underlying mechanisms of EDS, more effective treatments can be developed.

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Condition tags

endometriosis

MeSH descriptors

Ehlers-Danlos Syndrome Gynecology Obstetrics Collagen Female Humans Pregnancy

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References (32)

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