Deciduosis of the appendix

Saul Suster, S Suster, Suster S, C A Moran, César A. Moran, Moran CA
The American journal of gastroenterology · 1990 · vol. 85(7) , pp. 841–5 · PMID:2196785 · W71691653
Review OA: closed CC0 ⤵ 20 in-corpus citations
View on OpenAlex View on PubMed
⚙ AI-generated summary by qwen3.7-flash, 2026-08-21 ⓘ

This study characterizes six cases of appendiceal deciduosis in pregnant women, finding submesothelial decidualized cells without endometriosis that may explain acute appendicitis symptoms during pregnancy.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

A clinicopathologic and immunohistochemical study of six cases of deciduosis of the appendix is presented. The patients were pregnant women aged 18-40 years. In four cases, the patients presented with signs and symptoms of acute appendicitis during their 26th to 31st week of pregnancy; in the other two, the lesions were discovered incidentally in appendectomy specimens obtained during cesarean section and tubal ligation at term. Histologically, the lesions were characterized by the presence of multiple, irregularly distributed submesothelial deposits of decidualized cells in the serosa of the appendix, without any associated evidence of endometriosis. By immunohistochemistry, the decidualized cells strongly labelled with vimentin antibodies, consistent with their stromal origin. In two cases, coexpression of vimentin and desmin intermediate filaments was observed, suggestive of myoid differentiation. The possible relationship of the lesions with the development of symptoms of peritoneal irritation in these patients is discussed along with a review of the literature on the abdominal complications of ectopic decidua.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Appendicitis Decidua Pregnancy Complications Adolescent Adolescent Adult Adult Appendicitis Appendicitis Appendicitis Decidua Decidua Female Female Humans Humans Immunohistochemistry Immunohistochemistry Pregnancy Pregnancy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (17)

Source provenance

europepmc
last seen: 2026-10-14T06:08:39.101224+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-10-08T21:09:27.188120+00:00
License: CC0 · commercial use OK