HISTOPATHOLOGICAL SPECTRUM OF NON NEOPLASTIC AND NEOPLASTIC LESIONS OF UTEROCERVIX IN NORTH WEST RAJASTHAN

In: International Journal of Medical and Biomedical Studies · 2021 · vol. 5(6) · doi:10.32553/ijmbs.v5i6.1947 · W3167678135
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This study analyzed 148 hysterectomy specimens, finding leiomyoma and adenomyosis most common in the myometrium, while inflammatory lesions and chronic nonspecific cervicitis predominated in the cervix, with two cases of cervical carcinoma identified.

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This prospective histopathological study analyzed 148 hysterectomy specimens collected from a pathology department in North West Rajasthan between 2018 and 2020. The research identified leiomyoma and adenomyosis as the most prevalent findings in the myometrium, occurring in 79.73% and 43.92% of cases respectively, while chronic nonspecific cervicitis was the dominant cervical lesion. The authors note that histopathological examination remains the gold standard for diagnosing benign conditions and ruling out malignancy, confirming clinical diagnoses in the majority of cases. Relevance to endometriosis: adenomyosis is listed as a common finding in hysterectomy specimens, though the paper does not discuss endometriosis or provide specific data on its prevalence within this cohort.

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Abstract

Background: The female genital tract includes the uterine corpus, cervix, fallopian tubes and ovaries. Women worldwide suffer from gynaecologic and obstetric disorders that require hysterectomy as a treatment option. Hysterectomy is a definite treatment of pelvic pathology including fibroid, abnormal heavy bleeding, chronic pelvic pain, endometriosis, adenomyosis, uterine prolapse, pelvic inflammatory disease and cancer of reproductive organs. Hysterectomy specimens contribute a major component of histopathological work in Pathology laboratories. Methods: This is a prospective study carried out in the Department of Pathology, SPMC, Bikaner for two years from October 2018 to September 2020. All surgically excised hysterectomy specimens received by the department during study period were included in the study. Tissues were fixed and processed as per departmental protocols. Pieces taken from ectocervix, endocervix, uterine canal and fundus. Pieces also taken from any abnormal area. Tissue bits routinely processed 3 to 6 micron thick sections made from paraffin embedded blocks and were stained with H&E stain. Special stains will be done whenever necessary. Results: We included a total of 148 cases of hysterectomies received to our department during the study period in our study. Of total 148 cases, 87.83% hysterectomies were abdominal and 12.16% were vaginal and TAHBSO was the commonest procedure. In myometrium the most common finding was leiomyoma and adenomyosis with 79.73% and 43.92% cases respectively. In cervix, most cases were inflammatory lesions with chronic nonspecific cervicitis was the most common histopathological finding. Two cases (1.37%) of carcinoma cervix were reported. Conclusions: Most of the cases which underwent hysterectomy were for symptomatic untreatable benign conditions and few for malignancies. Majority of the cases were histopathologically consistent with clinical diagnosis. Histopathological examination and its correlative study with preoperative clinical diagnosis is very important. Thus, histopathological examination is still the gold standard test to diagnose and rule out malignancy and must be compulsory for all the surgical specimens. Keywords: Hysterectomy, Uterocervix, Pathology
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Background

The female genital tract includes the uterine corpus, cervix, fallopian tubes and ovaries. Women worldwide suffer from gynaecologic and obstetric disorders that require hysterectomy as a treatment option. Hysterectomy is a definite treatment of pelvic pathology including fibroid, abnormal heavy bleeding, chronic pelvic pain, endometriosis, adenomyosis, uterine prolapse, pelvic inflammatory disease and cancer of reproductive organs. Hysterectomy specimens contribute a major component of histopathological work in Pathology laboratories.

Methods

This is a prospective study carried out in the Department of Pathology, SPMC, Bikaner for two years from October 2018 to September 2020. All surgically excised hysterectomy specimens received by the department during study period were included in the study. Tissues were fixed and processed as per departmental protocols. Pieces taken from ectocervix, endocervix, uterine canal and fundus. Pieces also taken from any abnormal area. Tissue bits routinely processed 3 to 6 micron thick sections made from paraffin embedded blocks and were stained with H&E stain. Special stains will be done whenever necessary.

Results

We included a total of 148 cases of hysterectomies received to our department during the study period in our study. Of total 148 cases, 87.83% hysterectomies were abdominal and 12.16% were vaginal and TAHBSO was the commonest procedure. In myometrium the most common finding was leiomyoma and adenomyosis with 79.73% and 43.92% cases respectively. In cervix, most cases were inflammatory lesions with chronic nonspecific cervicitis was the most common histopathological finding. Two cases (1.37%) of carcinoma cervix were reported.

Conclusions

Most of the cases which underwent hysterectomy were for symptomatic untreatable benign conditions and few for malignancies. Majority of the cases were histopathologically consistent with clinical diagnosis. Histopathological examination and its correlative study with preoperative clinical diagnosis is very important. Thus, histopathological examination is still the gold standard test to diagnose and rule out malignancy and must be compulsory for all the surgical specimens.

Keywords

Hysterectomy, Uterocervix, Pathology Downloads Published Issue Section License Copyright (c) 2021 International Journal of Medical and Biomedical Studies This work is licensed under a Creative Commons Attribution 4.0 International License.

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endometriosisadenomyosischronic_pelvic_pain

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