The effect of vitamin D supplementation on the size of uterine leiomyoma in women with vitamin D deficiency.
article
OA: gold
CC0
⤵ 4 in-corpus citations
Abstract
BACKGROUND: The aim of this study was to evaluate the effect of vit D supplementation on the size of uterine leiomyoma in women with vit D deficiency. METHODS: This double-blind prospective clinical trial was performed on 69 patients with uterine leiomyomas who had vit D deficiency. Group A (n=35) was treated with vit D 50,000 IU every 2 weeks for 10 weeks, while group B (n=34) received placebo with same color and shape. Finally, the leiomyoma size in both groups was compared (IRCT: 20160521027998N5). RESULTS: levels were significantly higher in group receiving vitamin D (36.08 vs 16.25 ng/ml). (P<0.001) Leiomyomas size in vit D group significantly decreased as compared to placebo group (52.58 vs 61.11 mm, respectively). CONCLUSION: Our results showed that administration of vit D3 may reduce the size of leiomyoma. It seems that vitamin D administration is the effective way to treat leiomyoma.
My notes (saved in your browser only)
Citation neighborhood (sparse)
Too few in-corpus citations on either side for a chart; here are the lists.
Cites (3)
- Non-surgical management of leiomyoma: impact on fertility 2004
- 1,25-Dihydroxyvitamin D3 Regulates Expression of Sex Steroid Receptors in Human Uterine Fibroid Cells 2015
- EMAS position statement: Management of uterine fibroids 2014
Cited by (4)
- Vitamin D and uterine fibroid growth, incidence, and loss: a prospective ultrasound study 2022
- Marine Oligo-Fucoidan as a Safe Functional Food for Managing Uterine Fibroids: Results from a Pilot Randomized Controlled Trial 2025
- The Potential of Vitamin D and Epigallocatechin Gallate (EGCG) for the Treatment of Uterine Fibroids: Evidence From In Vitro to Clinical Studies 2025
- Comparative Plasma Levels of Vitamin D in Women with or withoutUterine Fibriods in Lagos State University Teaching Hospital, Ikeja,Lagos, Nigeria 2021
References (34)
- 1,25-Dihydroxyvitamin D3 Regulates Expression of Sex Steroid Receptors in Human Uterine Fibroid Cells via openalex
- EMAS position statement: Management of uterine fibroids via openalex
- Non-surgical management of leiomyoma: impact on fertility via openalex
- doi:10.1210/jc.2013-1777 via openalex
- doi:10.1095/biolreprod.111.098145 via openalex
- doi:10.1096/fj.10-172577 via openalex
- doi:10.2147/ijwh.s38800 via openalex
- W17469937 via openalex
- doi:10.3945/ajcn.111.016600 via openalex
- doi:10.1095/biolreprod.113.107714 via openalex
- doi:10.1016/j.fertnstert.2007.01.093 via openalex
- doi:10.1002/ijc.2910610611 via openalex
- doi:10.1080/14767058.2017.1406470 via openalex
- doi:10.1186/1471-2458-4-38 via openalex
- doi:10.1093/aje/kwt091 via openalex
- doi:10.3945/ajcn.113.073635 via openalex
- W2144802697 via openalex
- doi:10.1097/ede.0b013e31828acca0 via openalex
- doi:10.1089/jwh.2005.14.692 via openalex
- doi:10.1289/ehp.5787 via openalex
- doi:10.1016/s0015-0282(03)02207-6 via openalex
- doi:10.1177/1933719114537721 via openalex
- doi:10.1016/j.fertnstert.2008.02.136 via openalex
- doi:10.1210/jc.2004-0682 via openalex
- doi:10.1016/j.fertnstert.2010.07.1041 via openalex
- doi:10.1093/ajcn/76.1.187 via openalex
- doi:10.1111/j.1471-0528.2000.tb13330.x via openalex
- doi:10.1016/j.fertnstert.2015.05.031 via openalex
- doi:10.1080/09513590.2017.1391774 via openalex
- doi:10.1097/md.0000000000005698 via openalex
- doi:10.1126/science.1112063 via openalex
- doi:10.1007/s00774-007-0791-7 via openalex
- doi:10.1016/j.ajog.2013.07.017 via openalex
- doi:10.1056/nejmra070553 via openalex
Cited by (4)
- Marine Oligo-Fucoidan as a Safe Functional Food for Managing Uterine Fibroids: Results from a Pilot Randomized Controlled Trial 2025
- The Potential of Vitamin D and Epigallocatechin Gallate (EGCG) for the Treatment of Uterine Fibroids: Evidence From In Vitro to Clinical Studies 2025
- Vitamin D and uterine fibroid growth, incidence, and loss: a prospective ultrasound study 2022
- Comparative Plasma Levels of Vitamin D in Women with or withoutUterine Fibriods in Lagos State University Teaching Hospital, Ikeja,Lagos, Nigeria 2021
SciLite annotations
chemicals 21
vitamin d
vitamin d
vitamin d
vitamin d
previtamin d3
vitamin d
vitamin d
previtamin d3
vitamin d
paricalcitol
dibenzo[a,d][7]annulene
previtamin d3
licoricesaponin d3
licoricesaponin d3
annotemoyin 1
estrogen
chatenaytrienin 1
previtamin d3
d3 vitamins
vitamin d
estrogen
organisms 5
noordeloos 2009062
noordeloos 2009062
zitter rats
zitter rats
humans
Source provenance
- europepmc
- last seen: 2026-06-20T06:14:18.781669+00:00
- openalex
- last seen: 2026-05-10T10:47:34.939468+00:00
- scilite
- last seen: 2026-05-18T04:26:01.642840+00:00
License: CC0
· commercial use OK