Anticardiolipin and antihiston levels during the treatment of IVF patients with endometriosis by Goserelin

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This study investigated anticardiolipin and antihistone antibody levels in IVF patients with endometriosis undergoing Goserelin treatment.

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This paper reports measurements of anticardiolipin and antihistone antibody levels in IVF patients diagnosed with endometriosis who were treated with the gonadotropin-releasing hormone agonist goserelin, with the aim of tracking autoimmune-related antibody changes during treatment. The study appears to be a focused clinical investigation with antibody testing over the course of IVF management, rather than a broad mechanistic analysis. A key limitation is that the provided text includes only citation and bibliographic information without the detailed methods, cohort size, timing of blood sampling, or the magnitude of antibody changes, so the specific findings cannot be verified from the excerpt alone. Relevance to endometriosis: the paper’s title and study objective are explicitly about endometriosis in IVF patients undergoing goserelin treatment, and it is therefore centrally about endometriosis and immunologic antibody markers during therapy.

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References Dmowski WP, Braun D, Gebel H: Endometriosis: Genetic and immunologic aspects.In Current Concepts in Endometriosis. New York, Alan R. Liss, 1990, pp 99–122 Ventruba P, Crha I, Vlckova V, Vlasin Z: Anticardiolipin, antihistones and antinuclear antibodies in women with fertility disorders. Hum Reprod (Suppl 1) 1993;8:169 Harris EN, Ghavari AE: Evaluation of the anti-cardiolipin antibody test. Clin Exp Imunol 1986;68:215 Gompertz NR, Isenberg DA: Correlation between clinical features of SLE and levels of antihiston antibodies of the IgG, IgA and IgM isotypes. Ann Rheum Dis 1990;49:524–527 Gleicher N: Autoimmunity and Reproductive Failure.In Frontiers in Human Reproduction. Ann NY Acad Sci 1991;626:537–544 Ventruba P, Muller P, Mlyncek M, Crha I: Multicentric study of Zoladex in the treatment of endometriosis—Preliminary report. Int J Gynecol Obstet (Suppl 1) 1994;46:168 El-Roeiy A, Dmowski WP, Gleicher N: Danazol but not gonadotropin-releasing hormone agonists supreses autoantibodies in endometriosis. Fertil Steril 1988;50:864–871 Author information Authors and Affiliations Rights and permissions About this article Cite this article Crha, I., Ventruba, P. Anticardiolipin and antihiston levels during the treatment of IVF patients with endometriosis by Goserelin. J Assist Reprod Genet 13, 366–368 (1996). https://doi.org/10.1007/BF02070154 Received: Accepted: Issue date: DOI: https://doi.org/10.1007/BF02070154

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Condition tags

endometriosis

MeSH descriptors

Autoantibodies Cardiolipins Endometriosis Fertilization in Vitro Goserelin Histones Adult Autoantibodies Cardiolipins Endometriosis Endometriosis Female Goserelin Histones Humans

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