Evaluation of Endometriosis Risk Factors and Clinical Treatments in Bangladesh: A Cross-sectional Study. (Preprint)

BACKGROUND Endometriosis is a gynecological condition that involves the implantation of endometrial tissue outside the uterine cavity. About 1.2 million women are suffering from this disease in Bangladesh. OBJECTIVE The purpose of this study was to explore the risk factors, symptoms, and clinical treatment in Bangladesh METHODS In this cross-sectional study, out of 162 infertile women 82 had endometriosis confirmed with laparoscopy and 80 were included in the control group. All were asked to fill out a questionnaire containing demographics, reproductive, and menstrual status. Comparisons between the two groups were done using an Independent T-test, Chi-square test, and logistic regression model. RESULTS The prevalence of endometriosis was higher with, age, marital status, and BMI (P < 0.05). The most common symptoms were dysmenorrhea, excessive bleeding, cramping etc. Infertility (OR:2.21; %95CI: 1.07–4.53; P = 0.03), thyroid imbalance (OR:3.44; %95CI: 1.47–8.03; P = 0.004), irregular menstruation (OR:5.76; %95CI: 2.12–15.60; P = 0.001), age at menarche (OR:2.54; %95CI: 1.04–6.21; P = 0.04) and abortion (OR:2.75; %95CI: 1.31–5.74; P = 0.007) were associated with endometriosis risk. Endometriosis was diagnosed most frequently by TVS (transvaginal ultrasound) at 41.1%, NSAI (nonsteroidal aromatase inhibitors) at 22.8% was the most commonly utilized medicine, and 13.6% of patients undergo laparoscopy. CONCLUSIONS Endometriosis is a considerable public health issue because it affects many women and is associated with significant morbidity. In this study, we developed a model that can be used to predict the risk of endometriosis in infertile women in Bangladesh CLINICALTRIAL BRAC university Institutional Review Board (IRB) under the IRB number BRACUIRB_220240006